What Cream Can You Put on a Herpes Outbreak?

Herpes is a common viral infection caused by the herpes simplex virus (HSV), which can manifest as sores, often on the lips or genitals. While the virus remains in the body indefinitely, topical creams offer a primary approach to manage the discomfort and duration of outbreaks.

Understanding Topical Antiviral Options

Several topical antiviral creams are available to address herpes outbreaks, categorized by their accessibility. Prescription options, which require a doctor’s consultation, include acyclovir, often known by the brand name Zovirax, and penciclovir, sold as Denavir. These target the herpes virus to reduce outbreak severity and duration. They are typically prescribed for recurrent oral or genital herpes.

In contrast, over-the-counter (OTC) options provide more immediate access for individuals experiencing symptoms. Docosanol, commonly marketed as Abreva, is the most widely available OTC topical treatment for cold sores (oral herpes). This cream works differently from prescription antivirals, aiming to shorten healing time. The choice between prescription and OTC options often depends on the type, frequency, and severity of the herpes outbreak.

How These Creams Combat the Virus

Topical antiviral creams work by targeting the herpes simplex virus within the affected skin cells. Prescription antiviral creams, such as acyclovir and penciclovir, function as nucleoside analogs. This means they mimic the building blocks of viral DNA, and when incorporated into the virus’s genetic material, they prevent it from replicating effectively. By interfering with this replication, these creams reduce viral load and shorten outbreak duration.

Docosanol, an over-the-counter option, operates through a different mechanism. It works by preventing the virus from entering healthy cells. By modifying the cell membrane, docosanol makes it more difficult for the herpes virus to fuse with and infect uninfected cells. While not directly inhibiting replication, it limits viral spread to new cells, contributing to faster healing.

Applying Creams for Optimal Use

Effective application begins at the first sign of an outbreak, known as the prodrome stage. This early stage might involve tingling, itching, or a burning sensation before any visible sores appear. Applying the cream at the first symptoms can significantly improve outcomes and reduce outbreak severity and duration.

When applying the cream, ensure clean hands to prevent further infection or spread. A thin layer should be gently dabbed onto the affected area, covering developing lesions or symptomatic areas. Users should follow specific instructions regarding frequency and duration, which typically range from three to five times a day for four to ten days. Maintaining good hygiene, such as washing hands thoroughly before and after application and avoiding sharing personal items, helps prevent the virus from spreading.

Beyond Topical Creams: When to Seek Medical Advice

While topical creams are effective for managing many herpes outbreaks, professional medical advice becomes important in certain situations. Individuals experiencing frequent, severe, or widespread outbreaks should consult a healthcare provider. Similarly, if symptoms worsen despite consistent cream use, or if signs of a bacterial infection, such as fever or spreading redness, appear, medical attention is warranted. These situations may indicate a need for a different treatment approach.

A doctor can also provide a definitive diagnosis if herpes is suspected for the first time. For more challenging cases, oral antiviral medications may be prescribed, which work systemically to control the virus. Seeking medical guidance ensures the most appropriate and effective treatment plan is in place for an individual’s specific condition.