What Causes Thrush in Pregnancy?

Vaginal thrush, medically termed vulvovaginal candidiasis, is a common yeast infection that frequently occurs during pregnancy. This condition is caused by an overgrowth of a fungus known as Candida, with Candida albicans being the species responsible for the majority of cases. It is a fungal imbalance that naturally occurs in the body, not a sexually transmitted infection, and it is estimated that the likelihood of experiencing thrush doubles when pregnant. While uncomfortable, the infection is not known to cause harm to the developing fetus, but treatment is important for the pregnant individual’s well-being.

Recognizing Common Symptoms

A pregnant individual should look for several specific signs that distinguish thrush from the normal increase in vaginal discharge that occurs during pregnancy. The most noticeable symptom is persistent and intense itching or irritation around the entrance to the vagina and the outer genital area. This irritation is often accompanied by a distinct soreness and a burning sensation, which may feel worse during urination or sexual intercourse. The characteristic sign of candidiasis is the discharge itself, which is typically thick, white, and odorless, often described as having a cottage cheese-like texture. The surrounding skin may also appear reddened or swollen due to the inflammation. If these symptoms appear, a conversation with an obstetric provider is warranted to confirm the diagnosis.

The Physiological Reasons for Increased Risk

The heightened susceptibility to thrush during pregnancy is primarily a result of profound shifts in the reproductive and endocrine systems. The most significant factor is the dramatically elevated level of the hormone estrogen throughout gestation. High estrogen concentrations directly influence the vaginal environment by promoting the accumulation of glycogen in the epithelial cells of the vaginal wall. This increase in glycogen provides a rich, readily available food source for the Candida fungus, fueling its rapid proliferation. This process concurrently leads to a change in the vaginal pH balance, making the environment less acidic than it is normally. The typical acidic environment is maintained by beneficial bacteria, which keep the opportunistic Candida in check; however, the shift in pH creates conditions that are more favorable for yeast overgrowth.

Furthermore, the immune system undergoes natural adjustments during pregnancy to prevent the rejection of the fetus. This necessary immune modulation can result in a slightly dampened local immune response within the vaginal tract. The body’s reduced ability to keep the naturally occurring fungal population under strict control makes the pregnant individual more vulnerable to symptomatic infections. This combination of hormonal changes, increased glycogen, and altered immune surveillance creates a biological niche for the Candida fungus to thrive, making thrush a common complaint, particularly in the third trimester.

Safe Management and Treatment Options

Individuals who suspect they have thrush must consult their doctor or midwife before beginning any form of treatment, even if the medication is available without a prescription. The standard medical approach during pregnancy involves the use of topical or local treatments to minimize systemic absorption and potential fetal exposure. These preferred options include antifungal creams and pessaries (vaginal tablets) containing medications such as clotrimazole or miconazole. These topical agents are considered safe because they act directly at the site of the infection and are absorbed into the mother’s bloodstream at extremely low levels. Treatment regimens are typically a course of six days or longer, as short-course treatments may be less effective during pregnancy.

Oral antifungal medications, like fluconazole, are generally avoided during pregnancy, especially in the first trimester, due to concerns regarding potential risks to the fetus. In addition to prescribed treatments, several simple hygiene practices can support recovery and help prevent recurrence. Wearing loose-fitting clothing and cotton underwear promotes air circulation, which helps keep the area dry and inhibits yeast growth. Avoiding scented products, harsh soaps, and douching is also recommended, as these items can disrupt the delicate vaginal microenvironment further.