What Causes One Red Eye and Headache?

A red eye with a headache can indicate various underlying issues. While sometimes benign, it often signals conditions needing medical attention. Understanding these potential origins helps in recognizing when to seek professional evaluation. This article explores medical reasons for a unilateral red eye and headache.

Headache Disorders with Eye Involvement

Certain primary headache disorders can cause a red eye and other symptoms on the same side as head pain. Cluster headaches are an example, characterized by unilateral pain around or behind one eye, in the temple, or forehead. Attacks last 15 minutes to 3 hours, occurring multiple times daily, sometimes in cyclical patterns. Autonomic symptoms on the same side include a red, watery eye, nasal congestion, eyelid drooping, and facial sweating.

Paroxysmal hemicrania is a less common headache disorder similar to cluster headaches, with unilateral pain and autonomic features like eye redness and tearing. Attacks are shorter and more frequent, often over five times daily, and respond completely to indomethacin. Migraines are known for throbbing head pain, light sensitivity, and nausea; ocular symptoms can occur, but a distinct red eye is not a hallmark.

Eye Conditions Causing Pain and Headache

Some eye conditions can cause pain radiating to the head, leading to a headache and red eye. Acute angle-closure glaucoma is an emergency with sudden increased eye pressure, causing severe eye pain, redness, blurred vision, and halos. It can also trigger nausea, vomiting, and headache. Prompt treatment prevents vision loss.

Uveitis, inflammation inside the eye, causes eye pain, redness, and light sensitivity; its pain can contribute to a headache. Scleritis and episcleritis involve inflammation of the eyeball’s outer layer. Scleritis causes deep pain radiating to the forehead or jaw, with redness. Episcleritis has less pain and redness, often resolving. Corneal damage, like an abrasion or ulcer, causes intense eye pain, tearing, redness, and light sensitivity, which can induce a referred headache.

Other Underlying Causes

Other conditions can also present with a red eye and headache. Sinusitis, an inflammation or infection of the sinuses, can cause facial pain, pressure, and headache, sometimes with redness or swelling around the eye if severe. Optic neuritis, inflammation of the optic nerve, causes pain with eye movement, vision loss, and sometimes a headache; a prominent red eye is less common.

Temporal arteritis, or giant cell arteritis, affects head and neck arteries, common in older adults. It causes new-onset headache, scalp tenderness, and jaw pain. If eye arteries are affected, it can lead to vision changes, including sudden vision loss, and rarely a red eye. Carotid artery dissection, a rare condition, involves a tear in the carotid artery. It presents with sudden headache, neck pain, and sometimes Horner’s syndrome, though a distinct red eye is not a primary symptom.

When to Seek Medical Care

A red eye with a headache warrants medical evaluation, especially with concerning symptoms. Seek immediate medical attention for sudden severe eye pain or headache, particularly with blurred vision, double vision, or vision loss. Halos around lights, nausea, or vomiting also signal urgent care.

Additional warning signs include high fever, stiff neck, or recent eye or head trauma. If symptoms worsen rapidly, do not improve, or if you have a compromised immune system, consult a healthcare professional promptly. An accurate diagnosis is important for appropriate treatment and preventing complications.

Headache Disorders with Eye Involvement

Certain primary headache disorders frequently present with a red eye and other symptoms affecting the face and eye on the same side as the head pain. Cluster headaches are a prime example, characterized by severe, unilateral pain, often described as boring or piercing, typically localized around or behind one eye, in the temple, or forehead. These attacks are short-lived, usually lasting between 15 minutes and 3 hours, but they can occur multiple times a day, sometimes in cyclical patterns over weeks or months. Accompanying the pain are autonomic symptoms on the same side, such as a red, watery eye (lacrimation), nasal congestion or runny nose, eyelid drooping (ptosis), and sweating on the forehead or face.

Paroxysmal hemicrania is a less common headache disorder that shares similarities with cluster headaches, including unilateral pain and associated autonomic features like eye redness and tearing. However, these attacks are typically shorter in duration and occur more frequently, often more than five times a day. A distinguishing feature of paroxysmal hemicrania is its dramatic and complete response to the medication indomethacin. While migraines are generally known for throbbing head pain, light sensitivity, and nausea, some individuals experience a visual aura, such as flashing lights or blind spots, before or during an attack. A distinct red eye is not a typical hallmark of migraine, but ocular symptoms can occasionally be present as part of the broader neurological disturbance.

Eye Conditions Causing Pain and Headache

Some conditions originating within the eye itself can cause significant pain that radiates to the head, leading to a headache alongside a red eye. Acute angle-closure glaucoma is a medical emergency characterized by a sudden, sharp increase in intraocular pressure, leading to severe eye pain, redness, and blurred vision, often accompanied by halos around lights. This condition can also trigger nausea, vomiting, and a headache, which may be felt around the eye or more broadly in the head. Prompt treatment is necessary to prevent permanent vision loss due to damage to the optic nerve.

Inflammation inside the eye, known as uveitis, can also manifest with eye pain, redness, and increased sensitivity to light (photophobia). The pain from uveitis can sometimes spread to the surrounding areas, contributing to a headache. Scleritis and episcleritis involve inflammation of the white outer layer of the eyeball, with scleritis causing deep, intense, boring pain that may radiate to the forehead or jaw, alongside significant redness. Episcleritis presents with less severe pain and redness, often resolving on its own. Damage to the cornea, such as a corneal abrasion or ulcer, can cause intense eye pain, tearing, redness, and light sensitivity. The irritation and pain from these superficial injuries can be severe enough to induce a referred headache on the same side as the affected eye.

Other Underlying Causes

Beyond primary headache disorders and direct eye pathologies, other conditions can also present with a red eye and headache. Sinusitis, an inflammation or infection of the sinuses, particularly those located close to the eyes, can cause facial pain, pressure, and a headache. This pain might be localized around the affected sinus and can sometimes be accompanied by redness or swelling around the eye, especially if the infection is severe or spreading. Optic neuritis involves inflammation of the optic nerve, which transmits visual information from the eye to the brain. This condition typically causes pain with eye movement, vision loss, and sometimes a headache, though a prominent red eye is less common unless there is associated orbital inflammation.

Temporal arteritis, also known as giant cell arteritis, is a serious inflammatory condition affecting the arteries, particularly those in the head and neck. It is more common in older adults and can cause a severe, new-onset headache, scalp tenderness, and jaw pain during chewing. If the arteries supplying the eye are affected, it can lead to vision changes, including sudden vision loss, and may rarely involve a red eye due to ocular ischemia. Carotid artery dissection, a rare but serious condition, involves a tear in the wall of the carotid artery in the neck. It often presents with sudden, severe headache, neck pain, and sometimes symptoms like Horner’s syndrome, which can involve a constricted pupil and drooping eyelid on one side, though a distinct red eye is not a typical primary symptom.

When to Seek Medical Care

Experiencing a red eye alongside a headache warrants medical evaluation, especially if certain concerning symptoms are present. Seek immediate medical attention if you experience a sudden onset of severe eye pain or headache, particularly if accompanied by blurred vision, double vision, or any loss of vision. The presence of halos around lights, nausea, or vomiting alongside these symptoms also signals a need for urgent care.

Additional warning signs include a high fever, stiff neck, or recent trauma to the eye or head. If symptoms worsen rapidly, do not improve, or if you have underlying medical conditions such as a compromised immune system, it is prudent to consult a healthcare professional promptly. An accurate diagnosis from a doctor or ophthalmologist is important for receiving appropriate treatment and preventing potential complications.

References

Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 2013;33(9):629-808.
Cohen AS, Burns B, Goadsby PJ. Paroxysmal hemicrania: a case series of 31 patients. Brain. 2006;129(Pt 5):1106-14.
Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Ann N Y Acad Sci. 2017;1414(1):1-19.
Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014;311(18):1901-11.
Jabs DA, Rosenbaum JT, Foster CS, et al. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol. 2000;130(4):492-513.
Lemp MA, Foulks GN. The Eye and Systemic Disease. In: Yanoff M, Duker JS, eds. Ophthalmology. 4th ed. Mosby Elsevier; 2014:chap 8.
Rosenfeld RM, Piccirillo JF, Silvers SI, et al. Clinical practice guideline: adult sinusitis. Otolaryngol Head Neck Surg. 2007;137(3 Suppl):S1-31.
Stone JH, Calabrese L, Matteson EL. American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis. Arthritis Rheumatol. 2021;73(7):1094-1109.
Schievink WI. Spontaneous dissection of the carotid and vertebral arteries. N Engl J Med. 2001;344(12):898-906.

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