What Causes High Arsenic Levels in Urine?

Arsenic is a naturally occurring element found throughout the Earth’s crust, existing in various forms in soil, water, and air. Elevated levels can be a health concern. Urine tests are a common and reliable method to measure recent arsenic exposure.

Understanding Arsenic: Inorganic and Organic Forms

Arsenic exists in different forms: inorganic or organic. Inorganic arsenic compounds, which do not contain carbon, are more toxic and found in water, soil, and some foods. Organic arsenic compounds contain carbon and are less harmful, often passing through the body quickly. Organic arsenic is found in seafood. Urine tests can differentiate between these forms, which is important for understanding the source and potential health implications.

Common Sources of Arsenic Exposure

Contaminated drinking water is a common pathway for inorganic arsenic exposure. Private well water is a frequent source of concern, as it is not routinely tested by public agencies, and natural arsenic levels vary geographically. Arsenic can leach into water supplies from naturally occurring deposits in the ground.

Food is also a significant source of arsenic exposure, especially from crops that readily absorb it from soil and water. Rice and rice-based products are notable examples, as rice plants absorb more arsenic than other cereal crops, particularly when grown in flooded fields. Other foods like fruits and vegetables grown in contaminated soil can also contain arsenic.

Occupational exposure can also contribute to elevated arsenic levels. Professions like mining, smelting, glass manufacturing, and pesticide production involve working with arsenic compounds. Historically, arsenic was used in wood preservatives, and burning treated wood can release arsenic. Environmental factors, such as living near industrial sites or areas with high arsenic concentrations in bedrock, can also lead to exposure.

How Arsenic Enters and Exits the Body

Once arsenic is ingested or inhaled, it is absorbed into the bloodstream. The body attempts to process and eliminate arsenic, primarily through a detoxification process called methylation. During methylation, the body converts inorganic arsenic into various metabolites. These metabolized forms of arsenic are then primarily excreted from the body through the kidneys. They are subsequently found in urine, which is why urine tests are effective for measuring recent exposure. Most arsenic leaves the body within several days, although some can remain for a few months.

Addressing High Arsenic Levels

If a urine test indicates elevated arsenic levels, consulting a healthcare professional, such as a doctor or toxicologist, is a crucial first step for interpretation and guidance. They can help determine the type of arsenic and the potential health implications. Identifying and reducing the sources of exposure is a key strategy for managing high levels.

This involves testing private well water for arsenic contamination and evaluating dietary habits, especially consumption of foods known to accumulate arsenic like rice. Reviewing occupational exposures is also important for individuals in at-risk professions. General mitigation strategies include using filtered water, cooking rice with excess water and draining it, and diversifying one’s diet to reduce reliance on single food sources.