What Causes Fall Allergies? From Ragweed to Mold Spores

Fall allergies are a common seasonal experience, affecting many as warmer months transition to cooler temperatures. These reactions occur when the immune system responds to specific environmental substances prevalent during autumn. The body’s reaction to these airborne particles causes uncomfortable symptoms.

The Dominant Pollen Producers

The primary plant-based allergen responsible for fall allergies is ragweed, a widespread weed across the United States, particularly in the Midwest and on the East Coast. Ragweed plants typically begin releasing pollen in August and continue through November, with pollen levels often peaking in early to mid-September. A single ragweed plant can produce up to a billion lightweight pollen grains that travel hundreds of miles, making avoidance difficult. Pollen counts tend to be highest during the morning hours.

Other types of weed pollen also contribute to autumn allergic reactions, including pigweed, lamb’s quarters, cocklebur, sagebrush, mugwort, Russian thistle, and tumbleweed. These pollens become airborne, adding to the overall allergen load. Their presence and concentration vary by region, influencing symptom severity for sensitive individuals.

Mold’s Seasonal Surge

Beyond pollen, mold spores represent another significant cause of fall allergies. Outdoor mold thrives in damp conditions, making decaying leaf piles, compost, and other moist organic matter ideal breeding grounds. Mold growth is particularly prevalent in heat and high humidity, and its spores can become airborne and widespread in the environment.

Rainfall can significantly influence mold spore counts; while initial rain may wash away pollen, the increased moisture creates optimal conditions for mold proliferation, leading to higher spore levels. These spores are released into the air and, like pollen, can be inhaled, triggering allergic responses. Mold spore levels are generally highest from mid-summer through late fall, persisting until the first hard frost.

Other Contributing Factors

As temperatures drop and people spend more time indoors, other environmental factors can contribute to or worsen fall allergy symptoms. Indoor allergens such as dust mites and pet dander can become more concentrated in enclosed spaces. Dust mites, for example, thrive in warm, humid indoor environments, feeding on shed human and pet skin flakes.

Irritants in the air, such as smoke and various forms of air pollution, can also exacerbate respiratory symptoms that mimic or intensify allergic reactions. Pollutants like particulate matter, ozone, and nitrogen dioxide can irritate the respiratory tract, making the body more susceptible to allergens and promoting inflammation. This heightened sensitivity means that even small amounts of allergens can trigger significant responses, complicating the experience of fall allergies.

The Body’s Allergic Response

Allergic reactions occur because the immune system mistakenly identifies harmless environmental substances, known as allergens, as threats. Upon a person’s initial exposure to an allergen, the immune system becomes sensitized, producing specific antibodies called Immunoglobulin E (IgE). These IgE antibodies are designed to recognize the specific allergen in future encounters.

When re-exposed to the same allergen, these IgE antibodies trigger immune cells, primarily mast cells and basophils, to release various chemicals. The most notable of these chemicals is histamine. Histamine causes a cascade of effects, leading to common allergy symptoms such as sneezing, runny nose, itchy eyes, and congestion. This response is the body’s attempt to expel the perceived invader, even though the allergen itself poses no real danger.