What Causes Chronic Strep Throat?

Strep throat, a common bacterial infection, affects the throat and tonsils. It is caused by Group A Streptococcus bacteria, also known as Streptococcus pyogenes. Common symptoms include a sudden sore throat, fever, and sometimes white patches or streaks of pus on the tonsils. While a single episode of strep throat is typically treatable, some individuals experience repeated infections, leading to what is often referred to as “chronic” or “recurrent” strep throat.

Understanding Recurrent Strep Throat

Recurrent strep throat refers to multiple confirmed infections within a specific timeframe. It may be defined as seven or more episodes in one year, five or more in each of two consecutive years, or three or more episodes per year for three consecutive years. Each episode requires confirmation through laboratory testing, such as a rapid strep test or a throat culture, to ensure the presence of Group A Streptococcus. This is important because many conditions cause similar throat symptoms, and confirmation helps differentiate true recurrent strep from other frequent sore throats.

Bacterial Persistence and Incomplete Treatment

Streptococcus pyogenes bacteria can persist within the body, leading to repeated infections. One factor is not completing the full prescribed course of antibiotics. When treatment is stopped prematurely, some bacteria may survive and multiply, allowing the infection to re-emerge. Adhering to the full regimen is important, even if symptoms improve.

Another reason for persistence involves biofilm formation. Group A Streptococcus can form protective biofilms, particularly within the tonsils or other throat tissues. These biofilms are communities of bacteria encased in a self-produced matrix, making them more resistant to antibiotics and the body’s immune response. Bacteria can also “hide” deep within the folds and crypts of the tonsils, where they are difficult to eradicate. This protected environment allows the bacteria to remain in the body, potentially causing recurrent infections.

Reinfection from the Environment

External factors and re-exposure contribute to repeated strep throat infections. Individuals can carry the strep bacteria in their throat without symptoms, known as asymptomatic carriers. These carriers, often children or family members, can transmit the infection to others, leading to re-infection within a household or community. While generally less contagious than those with active symptoms, carriers can still be a source of spread.

Bacteria can also survive on surfaces, facilitating transmission through contaminated objects. Items such as doorknobs, toys, utensils, and toothbrushes can harbor the bacteria. Contact with these surfaces, followed by touching the nose or mouth, can lead to infection. Environments with close person-to-person contact, including schools, daycares, and crowded living spaces, facilitate spread among individuals. Practicing good hygiene, such as frequent handwashing and not sharing personal items, can help reduce this risk.

When Symptoms Might Not Be Strep

Recurrent sore throat symptoms are sometimes mistakenly attributed to strep throat when another cause is present. Many viral illnesses, such as the common cold, influenza, or mononucleosis, can cause sore throats with similar symptoms. These frequent viral infections can lead to the perception of chronic strep, though antibiotics are ineffective. Symptoms like a cough, runny nose, or hoarseness often suggest a viral cause.

Distinguishing between a strep carrier and an an active infection is important. A strep carrier tests positive for the bacteria but does not experience active symptoms or require antibiotics. Their positive tests might be misinterpreted as recurrent infections, even if symptoms are due to a viral illness. Accurate diagnosis through a throat swab for each episode is important to confirm Group A Streptococcus and guide appropriate treatment.

Environmental allergies, such as those causing post-nasal drip, or exposure to irritants like dry air, smoke, or pollution, can also cause chronic throat irritation and pain that mimics strep throat. Other types of bacteria, beyond Group A Streptococcus, can cause pharyngitis or tonsillitis, which might be misdiagnosed as strep. Proper diagnosis ensures the underlying cause of recurrent throat symptoms is identified and treated effectively.