What Can I Take for Shoulder Pain?

Shoulder pain is a common issue, often stemming from acute, non-traumatic events like muscle strain or mild overuse. While this article explores self-care and over-the-counter options for managing discomfort, this information is not a substitute for a professional medical diagnosis. If you have underlying health conditions or are taking other medications, consult a healthcare provider before starting any new pain regimen.

Over-the-Counter Oral Medications

The two main types of oral over-the-counter (OTC) pain relievers for shoulder pain are acetaminophen and Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), such as ibuprofen and naproxen. These medications offer different mechanisms for relief. Acetaminophen primarily works as an analgesic and antipyretic by inhibiting prostaglandin synthesis within the central nervous system, raising the pain threshold without directly targeting inflammation.

NSAIDs, including ibuprofen and naproxen, function by inhibiting the cyclooxygenase (COX) enzymes, which produce prostaglandins that cause inflammation, fever, and pain. By reducing these inflammatory chemicals, NSAIDs address pain caused by swelling and irritation in the shoulder joint or surrounding muscles. For most adults, the maximum OTC dose for ibuprofen is 1,200 mg per day, taken in doses of 200–400 mg every six to eight hours.

For acetaminophen, the maximum recommended daily dose is 3,000 to 4,000 mg, with individual doses ranging from 500 to 1,000 mg every four to six hours. Exceeding the maximum daily limit is associated with a risk of acute liver failure, as the liver’s metabolic pathways can become overwhelmed, leading to the accumulation of a toxic compound. NSAIDs also carry risks, notably gastrointestinal side effects like ulcers and bleeding, as well as cardiovascular and renal risks, which are reduced by using the lowest effective dose for the shortest duration.

Localized and Topical Relief Options

Topical analgesics, including creams, gels, and patches, deliver pain-relieving ingredients directly to the shoulder area. This method provides targeted relief while minimizing systemic side effects, such as gastrointestinal issues, associated with oral medications. These products often contain active ingredients that work locally to interrupt or distract from the pain signal.

Counterirritants like menthol and camphor create a cooling or warming sensation on the skin that acts as a distraction, overwhelming the nerve signals that carry the pain message. Methyl salicylate, also known as oil of wintergreen, is a counterirritant that produces a warming sensation and is related to the pain-relieving component of aspirin. Capsaicin, derived from chili peppers, works by causing a temporary burning sensation that, with repeated application, can desensitize the local nerve receptors responsible for pain transmission.

Non-Pharmacological Self-Care Strategies

Initial management of acute shoulder pain often involves drug-free strategies focused on controlling swelling and protecting the joint. The RICE principle—Rest, Ice, Compression, and Elevation—provides a framework for immediate self-care. Rest involves avoiding activities that aggravate the shoulder, allowing injured tissues time to stabilize and begin the healing process.

Cold therapy, or ice, is most beneficial during the first 24 to 72 hours following a sudden injury or flare-up, as it constricts blood vessels to reduce blood flow, swelling, and inflammation. Ice should be applied for 10 to 20 minutes at a time, several times a day, using a towel or cloth barrier to protect the skin from direct contact. Compression, such as using an elastic bandage, helps limit swelling, but ensure the wrap is not too tight, which could cause numbness or tingling.

Heat therapy dilates blood vessels to promote circulation and muscle relaxation. It is recommended only after the initial acute phase of swelling has subsided, typically after two or three days. Heat is effective for managing muscle stiffness, tension, or chronic, non-inflamed pain, and can be applied for 15 to 20 minutes, or longer for moderate stiffness. Gentle, pain-free range-of-motion exercises, such as pendulum swings or wall crawls, should be introduced early to prevent stiffness and maintain mobility. Correcting poor posture, especially during prolonged sitting or computer use, is also important for reducing chronic stress on the shoulder complex.

When Professional Medical Evaluation is Necessary

While many causes of shoulder pain respond well to self-care, certain symptoms act as “red flags” indicating that prompt medical attention is required. Immediate evaluation is necessary if you experience sudden, severe pain, especially following a fall or trauma, or if you notice an obvious deformity or misalignment of the shoulder joint.

Other serious signs include the inability to move the arm normally, a sudden loss of strength, or numbness or tingling extending down the arm or hand, which may suggest nerve involvement. If the pain is accompanied by systemic symptoms like fever, chills, or warmth and redness around the joint, an infection or other serious inflammatory condition may be present. Pain that persists or significantly worsens despite 7 to 10 days of consistent rest and self-care also warrants a medical assessment to identify the underlying cause. A physician typically begins with a physical examination and may order diagnostic imaging, such as X-rays or an MRI, to assess the bones, soft tissues, and joint structures.