What Can Cause Ankle and Knee Pain Without Injury?

The experience of pain simultaneously affecting both the ankle and knee without a clear, acute traumatic injury can be confusing. When trauma is absent, the discomfort signals underlying issues that have developed over time. This non-traumatic joint pain points toward either an internal disease process affecting multiple joints or chronic mechanical stress caused by long-term alignment problems. Understanding the source requires focusing on systemic conditions or cumulative biomechanical strain.

Systemic Inflammatory Conditions

One category of non-traumatic joint pain involves internal disease processes that cause inflammation throughout the body. These conditions are characterized by the immune system mistakenly attacking healthy tissues, including the lining of the joints. Rheumatoid Arthritis (RA) is a common example, where immune cells target the synovium, the soft tissue that lubricates and nourishes the joints. This systemic attack typically results in symmetrical joint involvement, often affecting both ankles and both knees simultaneously.

A defining feature of inflammatory arthritis like RA is morning stiffness that persists, frequently lasting longer than 30 minutes after waking. Unlike mechanical pain, which often improves with movement, RA-related pain may include noticeable warmth, redness, and swelling. Other autoimmune conditions, such as Psoriatic Arthritis or Lupus, can also cause widespread inflammation that settles in multiple joints. Gout, another inflammatory arthritis, arises from a metabolic disorder leading to a buildup of uric acid (hyperuricemia). When uric acid crystallizes, the deposits settle in joints, triggering sudden, intense episodes of pain and inflammation. While often affecting the big toe, gout can also manifest in the ankle and knee joints, causing rapid onset of severe pain and tenderness unrelated to injury.

Biomechanical Alignment and Kinetic Chain Stress

Another cause of simultaneous ankle and knee pain stems from chronic imbalances in the way the body moves and bears weight. The lower extremity functions as a kinetic chain, meaning a disturbance in the foot or ankle directly influences the mechanics of the knee and hip above it. Any misalignment in the ankle forces the knee to compensate during activities like walking or running.

Excessive foot pronation, or flat feet, is a common issue where the arch collapses and the foot rolls inward. This motion alters leg alignment by forcing the tibia to rotate internally. This rotation creates abnormal stress on the inner structures of the knee joint, often causing pain in the kneecap area or along the medial side of the knee. Over time, this repetitive stress can lead to chronic inflammation in both the knee and the compensating ankle joint. A lack of ankle flexibility, specifically limited dorsiflexion, can also trigger compensatory movements. When the ankle cannot move fully, the knee is forced to absorb more strain to maintain a normal walking pattern, leading to chronic strain and gait alterations.

Chronic Degenerative Changes and Lifestyle Factors

Long-term, non-inflammatory wear-and-tear conditions represent a distinct source of chronic pain. Osteoarthritis (OA) is the most prevalent, resulting from the gradual deterioration of the protective cartilage that caps the ends of the bones. This loss of cushioning leads to stiffness, pain, and a decreased range of motion that develops slowly. Unlike autoimmune arthritis, OA symptoms are typically worse with activity and improve with rest, though stiffness after periods of inactivity is common.

Excessive body weight accelerates the progression of OA in both the knees and ankles. Weight-bearing joints endure forces multiplied during movement; walking can exert three to six times a person’s body weight on the knee joint. This mechanical loading stresses joint structures, hastening cartilage breakdown. Carrying extra weight is also associated with a systemic factor, as fat tissue releases proteins that contribute to low-grade inflammation within the joints. Even modest weight loss yields significant benefits; losing just 5% of total body weight can lead to improvements in pain and joint function. Beyond weight, repetitive low-impact strain from occupational tasks or high-mileage activities can cause micro-trauma that contributes to cartilage degradation.

When to Seek Professional Diagnosis

While many forms of chronic joint pain can be managed with lifestyle adjustments, certain symptoms indicate the need for prompt medical evaluation. Any sudden, severe pain that makes it impossible to bear weight requires immediate attention. Visible joint deformity or the sensation of the joint locking or giving way are also red flags.

Systemic signs indicate that an underlying inflammatory or infectious process may be present. Joint pain accompanied by a fever, intense redness, warmth, or sudden, unexplained swelling warrants an urgent consultation with a healthcare provider. Pain or stiffness that persists for more than three days, or recurring joint symptoms within a month, suggests a chronic condition that needs accurate diagnosis. A primary care physician can initiate the evaluation and may refer patients to specialists, such as a rheumatologist for inflammatory conditions or an orthopedist for biomechanical and degenerative issues.