What Are the Signs of a Blood Clot After Knee Surgery?

A blood clot (thrombus) is a clump of blood components that form a solid mass within a blood vessel. While clotting is normal for stopping bleeding, a clot forming inside a vein can obstruct blood flow and cause serious complications. Following knee surgery, the primary concern is Deep Vein Thrombosis (DVT), where a clot forms in a deep vein, typically in the leg or pelvis. This risk is elevated for about three months post-procedure, often occurring between two and ten days after surgery. A DVT requires monitoring because it can lead to long-term leg problems or a life-threatening pulmonary embolism.

Recognizing Deep Vein Thrombosis (DVT) Symptoms

DVT symptoms usually manifest in the leg, often affecting only one limb. A noticeable sign is unilateral swelling, particularly in the calf, ankle, or foot. This swelling may be significantly more pronounced than expected post-operative puffiness and frequently fails to improve with elevation or ice, unlike typical surgical swelling.

Pain or tenderness may feel distinct from incision pain, often described as a deep cramp or persistent soreness. This discomfort typically worsens when standing, walking, or flexing the foot upward. The skin over the affected area may also become warm to the touch. Changes in skin color, such as redness, a darker hue, or bluish discoloration, might also be observed.

Another indicator of DVT is a feeling of tightness or heaviness in the leg, and the calf muscle might feel unusually firm or hard. While mild warmth and redness around the surgical site are normal during healing, DVT-related changes tend to extend beyond the immediate surgical area and are more intense. Because DVT symptoms can sometimes mimic a muscle strain, assessing the severity and persistence of these signs is an important step in recognizing a potential clot.

Identifying a Pulmonary Embolism (PE)

A Pulmonary Embolism (PE) occurs if a part of a DVT clot breaks away and travels through the bloodstream to lodge in the lung arteries. This blockage impedes blood flow and oxygenation, creating a medical emergency. PE symptoms are sudden in onset and primarily affect the chest and respiratory system.

The most common sign is a sudden onset of shortness of breath (dyspnea), which can occur even at rest. This may be accompanied by unexplained chest pain that is sharp or stabbing, frequently worsening when taking a deep breath. A rapid or irregular heartbeat (tachycardia) is also common as the heart attempts to compensate for reduced oxygen supply.

Other signs include a persistent cough, which may sometimes produce bloody mucus. Sudden dizziness, lightheadedness, or fainting might also occur, especially in severe cases. These symptoms indicate a potentially life-threatening situation and require an immediate emergency response.

Urgent Steps and When to Seek Emergency Care

Any suspicion of a blood clot, whether a DVT in the leg or a PE in the lung, requires immediate medical attention. For symptoms suggesting DVT, such as isolated leg swelling, pain, or redness, contact your surgeon’s office or healthcare team immediately. They will advise whether you should go to an urgent care facility or a hospital emergency room for diagnostic testing, such as an ultrasound, based on the severity of symptoms.

If you experience any signs of a Pulmonary Embolism (PE), such as sudden shortness of breath, chest pain, or rapid heart rate, call 911 or local emergency services immediately. Do not attempt to drive yourself to the hospital or wait for symptoms to resolve. These symptoms indicate a potentially life-threatening blockage requiring urgent evaluation and treatment.

Understanding the Mechanism and Prevention

The risk of a blood clot after knee surgery relates to three main factors, summarized by Virchow’s Triad: injury to the blood vessel wall, changes in blood flow, and alterations in clotting ability. Surgical trauma damages blood vessels, activating clotting mechanisms. The resulting inflammation and tissue repair contribute to an increased tendency for the blood to clot, known as hypercoagulation.

The most significant factor is reduced blood flow (stasis) caused by limited mobility during recovery. When leg muscles are not actively pumping, blood flows slowly in the deep veins, allowing clotting factors to accumulate. Prevention, therefore, centers on addressing these factors through a multi-modal approach.

Proactive measures begin with prescribed anticoagulant medications (blood thinners), which reduce the blood’s ability to form clots. Patients are also instructed to wear compression stockings or use sequential compression devices (SCDs). These devices apply pressure to the legs to improve circulation and prevent blood pooling. Early and monitored mobilization, such as short walks and ankle pump exercises, is considered one of the most effective strategies, as movement stimulates blood flow and prevents stasis.