What Are the Different Types of Isolation Precautions?

Isolation, in public health and healthcare, refers to measures designed to prevent the spread of infectious diseases. It separates sick or infected individuals from healthy ones to contain pathogens. These measures break the chain of transmission, safeguarding the community and healthcare workers. This strategy is a foundational component of infection control, limiting the spread of infectious agents.

Contact Precautions

Contact precautions are implemented for infections that can spread through direct physical contact with an infected person or indirect contact with contaminated surfaces or objects. This includes antibiotic-resistant organisms like Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridioides difficile (C. difficile), and skin infections such as scabies.

Measures involve rigorous hand hygiene, including washing hands or using alcohol-based rub before and after patient contact. Healthcare workers wear gloves and gowns upon entering and remove them before leaving to prevent cross-contamination. Patient-specific equipment, like stethoscopes or blood pressure cuffs, is often designated for exclusive use to minimize pathogen transfer. Regular disinfection of high-touch surfaces also reduces indirect transmission.

Droplet Precautions

Droplet precautions are employed for infections that spread through large respiratory droplets expelled when an infected individual coughs, sneezes, or talks. These heavy droplets travel short distances, usually up to six feet, before falling onto surfaces or mucous membranes. Diseases include influenza, mumps, rubella, and pertussis.

Interventions involve surgical masks for healthcare personnel working near the patient. Patients transported out of their room also wear a surgical mask to contain secretions. Hand hygiene remains a practice alongside mask use to reduce transmission from contaminated hands. These differ from airborne precautions because droplets do not remain suspended or travel long distances.

Airborne Precautions

Airborne precautions are reserved for infections spread by very small infectious particles that can remain suspended in the air for extended periods and travel over longer distances than droplets. These tiny particles, or droplet nuclei, can be inhaled by susceptible individuals even when not near the infected person. Diseases include Mycobacterium tuberculosis (tuberculosis), measles, and varicella (chickenpox).

Requirements include specialized respiratory protection, such as N95 respirators, designed to filter small particles. Respirators must be properly fitted for an effective seal. Patients are housed in Airborne Infection Isolation Rooms (AIIRs), or negative pressure rooms. These rooms maintain lower air pressure, ensuring air flows in and is exhausted outside or through a HEPA filter, preventing contaminated air escape.

Protective Isolation

Protective isolation, also called reverse isolation or neutropenic precautions, shields vulnerable patients from external infections. Unlike other isolation types that contain pathogens, it prevents pathogens from reaching immunocompromised individuals. Patients include those undergoing chemotherapy, organ transplant recipients, or individuals with severe burns, whose immune systems are weakened.

Measures create a clean, controlled environment around the patient. This often involves positive pressure rooms, where air flows out to prevent airborne contaminants from entering. Anyone entering, including staff and visitors, must adhere to strict hand hygiene and often wear PPE like masks, gowns, and gloves, even if asymptomatic. The goal is to minimize infectious agents in the patient’s space.

Community-Level Isolation

Community-level isolation refers to public health measures outside healthcare settings to control infectious disease spread. It encompasses two strategies: self-isolation and quarantine. Self-isolation is for individuals known to be sick or symptomatic, involving staying home and avoiding contact to prevent transmission. It is recommended when an individual has a diagnosis or suspects infection.

Quarantine applies to individuals exposed to a contagious disease but not yet symptomatic. Its purpose is to monitor for symptoms and prevent spread during the incubation period. Both rely on voluntary compliance and public health guidance, including symptom monitoring and avoiding public places. These interventions are crucial during outbreaks and pandemics to reduce infection rates and protect public health.


CDC. “Contact Precautions.” Centers for Disease Control and Prevention, 2023.
WHO. “Guidelines on infection prevention and control of epidemic- and pandemic-prone acute respiratory infections in health care.” World Health Organization, 2014.
CDC. “Scabies.” Centers for Disease Control and Prevention, 2022.
CDC. “Hand Hygiene in Healthcare Settings.” Centers for Disease Control and Prevention, 2023.
CDC. “Personal Protective Equipment (PPE) for Healthcare Personnel.” Centers for Disease Control and Prevention, 2023.
APIC. “Guide to the Elimination of MRSA Transmission in Healthcare Settings.” Association for Professionals in Infection Control and Epidemiology, 2015.
CDC. “Environmental Cleaning and Disinfection.” Centers for Disease Control and Prevention, 2023.
CDC. “Understanding How Germs Spread.” Centers for Disease Control and Prevention, 2022.
CDC. “Droplet Precautions.” Centers for Disease Control and Prevention, 2023.
CDC. “Guidance for Universal Masking.” Centers for Disease Control and Prevention, 2023.
CDC. “Infection Control Guidance for Healthcare Professionals about Coronavirus (COVID-19).” Centers for Disease Control and Prevention, 2023.
WHO. “WHO Guidelines on Hand Hygiene in Health Care.” World Health Organization, 2009.
CDC. “Airborne Precautions.” Centers for Disease Control and Prevention, 2023.
CDC. “Understanding How Germs Spread.” Centers for Disease Control and Prevention, 2022.
CDC. “Airborne Precautions.” Centers for Disease Control and Prevention, 2023.
CDC. “N95 Respirators and Surgical Masks.” Centers for Disease Control and Prevention, 2023.
CDC. “Respiratory Protection Program.” Centers for Disease Control and Prevention, 2023.
CDC. “Airborne Infection Isolation Rooms (AIIRs).” Centers for Disease Control and Prevention, 2023.
ASHRAE. “Healthcare Facilities Design Guide.” American Society of Heating, Refrigerating and Air-Conditioning Engineers, 2021.
NIH. “Protecting Immunocompromised Patients.” National Institutes of Health, 2020.
CDC. “Infection Prevention and Control for Immunocompromised Patients.” Centers for Disease Control and Prevention, 2023.
ASHRAE. “Healthcare Facilities Design Guide.” American Society of Heating, Refrigerating and Air-Conditioning Engineers, 2021.
CDC. “Personal Protective Equipment (PPE) for Healthcare Personnel.” Centers for Disease Control and Prevention, 2023.
NIH. “Protecting Immunocompromised Patients.” National Institutes of Health, 2020.
CDC. “Isolation and Precautions for People with COVID-19.” Centers for Disease Control and Prevention, 2023.
WHO. “Q&A: Quarantine and isolation.” World Health Organization, 2020.
CDC. “Quarantine and Isolation.” Centers for Disease Control and Prevention, 2023.
WHO. “Q&A: Quarantine and isolation.” World Health Organization, 2020.
CDC. “Quarantine and Isolation.” Centers for Disease Control and Prevention, 2023.
WHO. “Non-pharmaceutical public health measures for mitigating the risk and impact of epidemic and pandemic influenza.” World Health Organization, 2019. Isolation, in the context of public health and healthcare, refers to measures designed to prevent the spread of infectious diseases. Its fundamental purpose involves separating individuals who are sick or infected from healthy individuals to contain pathogens. These control measures are systematically implemented to break the chain of transmission, thereby safeguarding the broader community and healthcare workers from potential exposure. This strategy is a foundational component of infection control protocols, aiming to limit the dissemination of various infectious agents.

Contact Precautions

Contact precautions are implemented for infections that can spread through direct physical contact with an infected person or indirect contact with contaminated surfaces or objects within their environment. This category encompasses a range of pathogens, including antibiotic-resistant organisms like Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridioides difficile (C. difficile), which causes severe diarrhea. Skin infections such as scabies also necessitate contact precautions due to their direct transmissibility.

The primary measures for contact precautions involve rigorous hand hygiene, which includes washing hands with soap and water or using an alcohol-based hand rub before and after patient contact. Healthcare workers must don gloves and gowns upon entering the patient’s room and remove them before leaving to prevent cross-contamination. Additionally, patient-specific equipment, such as stethoscopes or blood pressure cuffs, are often designated for exclusive use to minimize the risk of pathogen transfer between patients. Regular disinfection of high-touch surfaces in the patient’s environment also plays a significant role in reducing indirect transmission.

Droplet Precautions

Droplet precautions are employed for infections that spread through large respiratory droplets expelled when an infected individual coughs, sneezes, or talks. These droplets are relatively heavy and typically travel short distances, usually up to about six feet or two meters, before falling out of the air and landing on surfaces or mucous membranes of a susceptible person. Diseases requiring droplet precautions include common infections such as influenza, mumps, rubella, and pertussis (whooping cough).

The main intervention for droplet precautions involves the use of surgical masks by healthcare personnel when working within the designated distance of the patient. Patients who are being transported out of their room are also often asked to wear a surgical mask to contain their own respiratory secretions. Hand hygiene remains a foundational practice alongside mask use to further reduce the risk of transmission from contaminated hands to mucous membranes. These precautions differ from airborne precautions because the droplets do not remain suspended in the air for extended periods or travel over long distances.

Airborne Precautions

Airborne precautions are reserved for infections spread by very small infectious particles that can remain suspended in the air for extended periods and travel over longer distances than droplets. These tiny particles, known as droplet nuclei, can be inhaled by susceptible individuals even when they are not in the immediate vicinity of the infected person. Examples of diseases requiring airborne precautions include highly contagious pathogens like Mycobacterium tuberculosis (which causes tuberculosis), measles, and varicella (chickenpox).

The unique requirements for airborne precautions include the use of specialized respiratory protection, such as N95 respirators or higher-level personal protective equipment, which are designed to filter out very small particles. These respirators must be properly fitted to ensure an effective seal around the wearer’s face. Patients with airborne infections are typically housed in Airborne Infection Isolation Rooms (AIIRs), also known as negative pressure rooms. These rooms are engineered to maintain a lower air pressure inside compared to adjacent areas, ensuring that air flows into the room and then is exhausted directly outside or through a high-efficiency particulate air (HEPA) filter, preventing contaminated air from escaping into general hospital corridors.

Protective Isolation

Protective isolation, sometimes referred to as reverse isolation, serves a distinct purpose: to shield highly vulnerable patients from potential infections from their external environment. Unlike other isolation types that contain a patient’s infection, protective isolation aims to prevent pathogens from reaching an immunocompromised individual. Patients who might require this heightened level of protection include those undergoing intensive chemotherapy, organ transplant recipients, or individuals with severe burns or leukemia, whose immune systems are significantly weakened.

The measures implemented in protective isolation are designed to create a clean, controlled environment around the patient. This often involves housing them in positive pressure rooms, where air flows out of the room to prevent airborne contaminants from entering. Anyone entering the room, including healthcare staff and visitors, must adhere to strict hand hygiene protocols and often wear personal protective equipment such as masks, gowns, and gloves, even if they are not exhibiting symptoms of illness. The goal is to minimize the introduction of any potential infectious agents into the patient’s immediate space.

Community-Level Isolation

Community-level isolation refers to public health measures implemented outside of traditional healthcare settings to control the spread of infectious diseases across a population. This encompasses two distinct but related strategies: self-isolation and quarantine. Self-isolation is specifically for individuals who are known to be sick with a contagious disease or are experiencing symptoms, and it involves staying home and avoiding contact with others to prevent further transmission. This measure is typically recommended when an individual has received a diagnosis or strongly suspects they are infected.

In contrast, quarantine is applied to individuals who have been exposed to a contagious disease but are not yet symptomatic and may or may not become ill.