What Are the Causes of Back Pain With Fever?

The simultaneous occurrence of back pain and fever often signals an underlying systemic issue, typically an infection, which requires prompt medical evaluation. Fever indicates the body’s immune system is fighting a pathogen. When paired with significant back pain, the infection source may be located near or within the spine or a major organ. This combination is a medical red flag because potential causes can lead to rapid deterioration, organ damage, or long-term neurological complications if not swiftly diagnosed and treated.

Infections of the Urinary Tract and Kidneys

The most common urgent cause of back pain accompanied by fever is Pyelonephritis, a bacterial infection of the kidneys. This condition usually begins as a lower urinary tract infection (UTI) where bacteria ascend the ureters to infect the upper urinary system. The resulting inflammation and swelling of the kidney tissue cause pain distinctively felt in the flank area, between the lower ribs and the hip, often on only one side. This flank pain can range from a dull ache to an intense, throbbing sensation that does not improve with changes in position.

Pyelonephritis is a systemic illness causing general body symptoms. A high fever, often exceeding 101°F, is typical, along with shaking chills, nausea, and vomiting. These systemic symptoms help distinguish kidney pain from common muscular back strain. The infection is frequently accompanied by lower urinary tract symptoms, such as dysuria (painful urination), frequent urges to urinate, and sometimes hematuria (blood in the urine).

Pyelonephritis is urgent due to the risk of progressing to urosepsis, where bacteria enter the bloodstream and cause a life-threatening reaction. Prompt diagnosis and treatment with antibiotics are necessary to prevent kidney damage. The back pain is caused by the inflammation and swelling of the renal capsule, which irritates the surrounding tissues and activates pain receptors. This type of kidney-related back pain is constant and non-stop, contrasting with the intermittent nature of many mechanical back issues.

Infectious Conditions Affecting the Spine

A less common but serious category involves infections localized directly within the spinal structure, causing severe, persistent back pain with fever. These infections include Vertebral Osteomyelitis (infection of the spinal bone), Discitis (infection of the intervertebral disc space), and Spinal Epidural Abscess. All pose a risk of permanent neurological damage. These conditions are typically caused by bacteria traveling through the bloodstream from a distant site, such as a skin or urinary tract infection, to seed the spine.

The pain associated with these structural infections is usually sharp, localized, and unrelenting. It is often described as deep aching that is severely worsened by movement or position changes. Unlike a muscle strain, this pain tends to be constant and may intensify at night, frequently occurring in the lumbar region. The infected site may be tender to the touch, and the patient may experience muscle spasms near the affected area.

A Spinal Epidural Abscess is a collection of pus surrounding the spinal cord and is considered a surgical emergency. It may arise from the progression of Osteomyelitis or Discitis, or from an infection elsewhere. While the classic presentation includes fever, back pain, and neurological decline, the first two symptoms often precede nerve damage. Compression from the abscess can quickly lead to nerve root irritation, causing radicular symptoms, such as shooting pains down the arms or legs.

Systemic Infections Causing Generalized Back Pain

In some cases, back pain accompanying a fever is not the result of a localized organ or spinal infection, but rather a symptom of a widespread systemic illness. Many severe viral or bacterial infections cause generalized muscle aching and soreness throughout the body. The large muscles of the back are often affected, leading to diffuse back pain.

Viral illnesses such as influenza or other respiratory infections frequently present with high fevers, chills, and profound body aches, including the back. This pain is generally symmetrical and described as a deep soreness, lacking the specific flank tenderness of a kidney infection or the sharp, localized pain of a spinal infection. The back pain in these scenarios is part of the body’s inflammatory response, not the site of the infection itself.

Bacteremia, or the presence of bacteria in the bloodstream, can also cause widespread inflammatory symptoms, including fever and generalized muscle pain. While bacteremia can lead to localized infections like Osteomyelitis, initially it may present with non-specific back pain as part of total body malaise. This discomfort is typically accompanied by fatigue, headache, and overall weakness, and usually resolves as the underlying systemic infection is treated and the fever subsides.

Critical Warning Signs and Emergency Care

Any instance of back pain combined with a fever requires medical attention, but certain symptoms require immediate emergency care. These “red flag” symptoms suggest severe complications like spinal cord compression or the onset of sepsis, a life-threatening response to infection. Neurological changes are particularly concerning and include the sudden onset of weakness, numbness, or tingling in the legs or groin area.

The most urgent neurological signs are loss of control over the bladder or bowels, or difficulty urinating, which can indicate Cauda Equina Syndrome caused by severe nerve compression from a spinal abscess. Signs of systemic shock or sepsis also warrant emergency intervention, such as rapid heart rate, fast breathing, confusion, or cold, clammy skin. A fever not controlled by medication or accompanied by severe, unrelenting pain should also be evaluated urgently.

A medical professional will conduct a thorough assessment, including laboratory tests to identify the infectious source and severity. Diagnostic tools include:

  • Initial blood work, including a Complete Blood Count (CBC) and inflammatory markers like C-reactive protein (CRP) and Erythrocyte Sedimentation Rate (ESR).
  • Blood cultures and urinalysis to identify the specific bacteria causing the infection.
  • Magnetic Resonance Imaging (MRI), which is the most effective tool for visualizing soft tissues and detecting early signs of spinal infections like Discitis or Epidural Abscess.
  • Computed Tomography (CT) scans, which may be used to evaluate the spine or other abdominal structures depending on the suspected cause.