What Are CHG Wipes and How Do You Use Them?

Chlorhexidine Gluconate (CHG) wipes are pre-moistened, disposable cloths used for medical-grade skin cleansing. The active ingredient, chlorhexidine gluconate, is a powerful antiseptic formulated to kill germs on the skin’s surface. Healthcare providers use these wipes as part of a regimen to significantly reduce the risk of infection. They offer a simple, convenient method for applying this cleansing agent to the entire body.

The Purpose of CHG Wipes

These wipes are primarily used in healthcare settings due to their function as a broad-spectrum antiseptic that targets bacteria, fungi, and certain viruses. The chlorhexidine gluconate solution not only provides immediate germ-killing action but also binds to the skin’s outer layer, offering a residual effect that continues to work for up to 24 hours after application. This sustained antimicrobial activity is what makes them highly effective in infection control.

The most common application is to prevent healthcare-associated infections (HAIs), which can occur during a hospital stay. They are a routine measure to reduce the risk of surgical site infections (SSIs) by decreasing the bacteria count on the skin before an operation. Daily bathing with CHG wipes is also a standard practice for patients with medical devices, such as central venous catheters, to minimize the risk of central line-associated bloodstream infections (CLABSIs). By removing harmful bacteria, CHG wipes help prevent those microbes from entering the body through incisions or device entry points.

Proper Application Technique

Applying the wipes correctly ensures the antiseptic solution can work effectively on the skin. If you are instructed to use CHG wipes before a procedure, you will often be asked to complete the application twice: once the night before and again the morning of the event. Before starting, you should wash your face and hair with regular soap and shampoo, rinse thoroughly, and then wait at least 15 minutes to allow your skin to cool and dry completely.

The correct method involves using a fresh wipe for each major section of the body to avoid spreading germs. Using a gentle, circular, or back-and-forth motion, wipe the entire body from the neck down, including underarms, groin folds, and between toes, while avoiding sensitive areas. A common regimen for an adult uses six wipes to cover the neck, chest, abdomen, arms, hips, groin, back, buttocks, and legs. After applying the solution, do not rinse or towel-dry the skin. The skin must be allowed to air dry completely to ensure the antiseptic remains on the skin and provides its protective effect.

Important Safety Considerations

A primary rule is to avoid using the wipes on or near sensitive mucous membranes, including the eyes, ears, mouth, and internal genital areas. Accidental contact can cause irritation, and if it occurs, the area should be rinsed immediately with clean water.

The wipes should never be used on open wounds, broken skin, burns, or areas with a rash, as this can lead to excessive absorption or irritation. While rare, a severe allergic reaction to chlorhexidine gluconate is possible; immediately notify a healthcare provider if you experience hives, itching, or difficulty breathing. Common side effects are minor, such as a mild rash, skin irritation, or a temporary sticky feeling on the skin as the solution dries. You should not apply any lotions, powders, or deodorants after using the wipes, as certain ingredients can inactivate the CHG.