Learn how the IDH1 R132H mutation alters enzyme function to drive cancer, creating a specific vulnerability that can be addressed by targeted therapies.
Learn how the Y402H variant in the CFH gene alters immune regulation, increasing the risk for age-related vision loss and what this means for your health.
Learn how Fourier Shell Correlation provides a robust quality assessment for 3D maps, revealing data reliability that goes beyond a single resolution number.
Discover a modeling method that uses gradual transitions and energy principles to simulate how complex material structures naturally change and evolve.
Vaping introduces nicotine to the brain, affecting its chemical signaling for mood, focus, and impulse control, leading to lasting functional adaptations.
Explore the critical role of proteasomes in maintaining cellular balance, from clearing out molecular waste to precisely controlling life's core functions.
Learn how the enzyme AID edits antibody genes, a crucial process that allows our immune system to mature its response and build long-term immunological memory.
Explore the methodical construction of fatty acids, from the transport of molecular precursors to their cyclical assembly by a tightly regulated enzyme system.
Explore the biological pathway turning old blood cells into biliverdin and bilirubin, a process central to understanding liver function and overall health.
Explore the body's immediate physiological response to vessel injury, where circulating cells rapidly form a temporary plug to manage initial blood loss.
Explore PhiC31 integrase, a tool for stable, large-scale gene addition, and understand its balance between efficient integration and off-target safety concerns.
While sweating is a primary human cooling method, it's rare in nature. Discover the diverse physiological and behavioral adaptations animals use to stay cool.