Musculocutaneous Nerve Injury: Causes, Symptoms, & Treatment

The musculocutaneous nerve is part of the upper arm’s nervous system, involved in both movement and sensation. It emerges from a network of nerves near the shoulder, known as the brachial plexus. This nerve primarily controls the muscles responsible for bending the elbow and rotating the forearm. It also provides feeling to a specific area of the forearm, important for daily arm functions.

Understanding the Musculocutaneous Nerve

The musculocutaneous nerve originates from the lateral cord of the brachial plexus. From its origin in the axilla, it travels distally and laterally, often piercing the coracobrachialis muscle. This nerve continues its path between the biceps brachii and brachialis muscles, supplying motor innervation to all three muscles in the anterior compartment of the arm: the coracobrachialis, biceps brachii, and brachialis.

The coracobrachialis muscle helps flex and adduct the shoulder joint. The biceps brachii is responsible for flexing the elbow and supinating (rotating outward) the forearm. The brachialis muscle, located beneath the biceps, is the primary flexor of the elbow joint. After innervating these muscles, the musculocutaneous nerve continues into the forearm as the lateral antebrachial cutaneous nerve, providing sensation to the skin on the outer side of the forearm from the elbow to the wrist.

Causes and Signs of Musculocutaneous Nerve Injury

Musculocutaneous nerve injuries can result from direct trauma, compression, or repetitive strain. Direct trauma, such as cuts, fractures of the humerus, or shoulder dislocations, can physically damage the nerve. For example, anterior shoulder dislocations may compress or stretch the nerve.

Compression can occur from prolonged pressure, such as improper positioning during sleep, or from anatomical structures like the biceps aponeurosis. Overuse or repetitive activities, particularly those involving forceful elbow extension and forearm pronation, can lead to stretching or compression. Iatrogenic injuries during medical procedures like shoulder surgery or internal fixation of the humerus are additional causes.

Signs of musculocutaneous nerve injury include weakness or difficulty with elbow flexion and forearm supination. Patients may experience numbness, tingling, or a burning sensation along the lateral aspect of the forearm, extending to the wrist. In chronic cases, muscle atrophy of the affected biceps brachii and brachialis muscles may become noticeable.

Diagnosing and Treating Musculocutaneous Nerve Injury

Diagnosing a musculocutaneous nerve injury begins with a physical examination. A healthcare provider will assess muscle strength in elbow flexion and forearm supination, check sensation in the lateral forearm, and evaluate reflexes, such as the biceps tendon reflex. Weakness in these movements and altered sensation are key indicators of injury.

To confirm the diagnosis and determine the extent of nerve damage, specialized tests are performed. Nerve conduction studies (NCS) measure how quickly electrical signals travel along the nerve, while electromyography (EMG) assesses the electrical activity of muscles at rest and during contraction. These tests can help pinpoint the exact location and severity of the injury, and differentiate it from other conditions like cervical spine nerve root impingement or biceps tendon rupture. Imaging studies, such as MRI, may also be used to visualize the nerve and surrounding tissues, identifying compression or muscle changes like edema or fatty atrophy.

Treatment for musculocutaneous nerve injury varies based on the cause and severity. Non-surgical approaches are often used for milder injuries, involving rest and activity modification to avoid aggravating movements. Physical therapy is frequently prescribed to maintain range of motion and strengthen affected muscles. Pain management may include non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids.

If conservative treatments are unsuccessful or if the injury is severe, such as a complete nerve transection, surgical intervention may be necessary. Surgical options include nerve repair, nerve grafting, or nerve decompression to relieve pressure on the nerve.

Recovery and Rehabilitation

Recovery from a musculocutaneous nerve injury can be prolonged, with timelines varying based on severity and type. Incomplete injuries or those involving demyelination (where the nerve’s protective sheath is damaged) generally have a better outlook than complete axonal injuries. Nerve regeneration occurs at about one millimeter per day.

Rehabilitation is central to recovery, involving both physical and occupational therapy. Physical therapy focuses on exercises to strengthen the biceps brachii and brachialis muscles, improve elbow flexion and forearm supination, and increase arm range of motion. Occupational therapy helps individuals adapt to daily activities and regain functional independence.

Sensory re-education exercises may be used to help the brain relearn how to interpret sensations from the affected forearm. While some patients may achieve full recovery, others might experience long-term deficits, depending on factors such as age and the extent of the initial damage. Early diagnosis and consistent adherence to the prescribed treatment and rehabilitation plan are important for optimizing outcomes and minimizing permanent impairment.

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