Low Bacteroidetes: Causes, Health Effects, and Solutions

The human gut harbors a vast and diverse community of microorganisms, collectively known as the gut microbiota. Among these, Bacteroidetes are one of the most abundant and well-studied groups of bacteria. This phylum, often comprising about 30% of the gut microbiota, plays a significant role in maintaining the health and balance of the digestive system. Their presence indicates a healthy gut ecosystem, influencing various bodily functions.

The Role of Bacteroidetes in the Gut

Bacteroidetes are highly efficient at breaking down complex carbohydrates, such as dietary fiber, that human enzymes cannot digest independently. This process of fermentation yields short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate. These SCFAs serve as a primary energy source for the cells lining the colon, supporting gut barrier integrity and influencing metabolic health.

Beyond energy production, Bacteroidetes contribute to nutrient absorption and modulate the host’s immune system. They assist in bile acid metabolism and help prevent harmful pathogens from colonizing by competing for nutrients and producing antimicrobial compounds. Specific species, like Bacteroides fragilis and Bacteroides thetaiotaomicron, are important for maintaining gut balance.

Factors Contributing to Reduced Bacteroidetes

Low levels of Bacteroidetes often point to an imbalance in the gut microbiota, known as dysbiosis. A diet low in fiber and high in processed foods can reduce their populations, as insufficient intake of diverse fiber sources limits the necessary fuel for these beneficial microbes.

Antibiotic use is another common cause of reduced Bacteroidetes, as these medications can indiscriminately kill off beneficial bacteria along with harmful ones. Chronic stress can also negatively impact gut microbial diversity, potentially leading to lower Bacteroidetes levels. Certain medical conditions and lifestyle choices, such as inadequate sleep, can further contribute to an imbalanced gut environment.

Health Effects of Low Bacteroidetes

Insufficient Bacteroidetes levels can lead to health issues due to the disruption of their beneficial functions. This imbalance can manifest as digestive problems, including bloating, gas, constipation, and diarrhea. The impaired breakdown of dietary fibers and reduced SCFA production can hinder nutrient absorption.

Low Bacteroidetes levels have been linked to metabolic health concerns, such as obesity, insulin resistance, and dyslipidemia. Their depletion can disrupt energy balance and storage within the body. Reduced Bacteroidetes have also been associated with increased gut inflammation, immune system dysregulation, and a higher risk of inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis.

Supporting Healthy Bacteroidetes Levels

To support and increase Bacteroidetes populations, dietary interventions are effective. Increasing the intake of diverse fiber-rich foods is important, as these provide the necessary fuel for these bacteria. Examples include fruits, vegetables, whole grains, legumes, and nuts. Incorporating prebiotic fibers like inulin and pectin, found in foods such as onions, garlic, and artichokes, can further promote their growth.

Consuming fermented foods like sauerkraut, kimchi, miso, kefir, and yogurt can introduce beneficial microorganisms that support a healthy gut environment. While specific probiotic recommendations should be discussed with a healthcare provider, certain probiotic strains may also contribute to rebalancing the gut microbiota. Beyond diet, lifestyle factors such as managing stress and ensuring adequate sleep can also foster a more diverse and balanced gut microbiome.

Is Fungi Considered a Plant? The Key Biological Reasons

What Is a Diauxic Growth Curve in Microbiology?

What Are Bacteriophage Supplements and How Do They Work?