LGG, or Lactobacillus rhamnosus GG, is a widely researched and popular probiotic strain recognized for its beneficial contributions to human health. As a type of beneficial microorganism, it plays a role in supporting the body’s internal balance. This particular strain has gained attention for its potential to positively influence various bodily functions, particularly within the gastrointestinal system.
Understanding LGG Probiotic
LGG, or Lactobacillus rhamnosus GG, is a specific bacterial strain. It was first isolated in 1983 from the intestinal flora of a healthy human by Sherwood Gorbach and Barry Goldin, from whom the “GG” designation originates. This bacterium can survive the harsh, acidic conditions of the stomach and the bile in the small intestine.
The strain Lactobacillus rhamnosus GG is also known by its American Type Culture Collection (ATCC) accession number 53103. Its robustness allows it to adhere to intestinal epithelial cells and temporarily colonize the gut. This characteristic enables it to exert its beneficial effects within the digestive tract.
How LGG Probiotic Interacts with the Body
LGG probiotics exert their effects through several mechanisms once introduced into the body. One primary way is by competing with harmful bacteria for nutrients and attachment sites along the gut lining, thereby hindering the growth of undesirable microorganisms. This competitive exclusion helps maintain a balanced gut microbiota.
The strain also interacts directly with host cells, influencing the gut environment. LGG produces lactic acid and antimicrobial compounds that discourage pathogen proliferation. It also stimulates reactions in the gut that improve the function of tight junctions. These tight junctions form a barrier that helps prevent harmful compounds from leaking into the bloodstream.
LGG also modulates the immune system. It binds to proteins on immune cells, signaling the body to release chemicals that regulate immune responses. This interaction extends to stimulating epithelial cell survival and mitigating mucosal inflammation. LGG’s influence on the gut mucosa and immune system contributes to maintaining intestinal homeostasis and immune tolerance.
Health Benefits of LGG Probiotic
LGG has demonstrated several scientifically supported health benefits, particularly concerning digestive health. It is effective in managing various forms of diarrhea, including those caused by rotavirus in children, antibiotic use, and traveler’s diarrhea. Supplementation with LGG can reduce the incidence and duration of these diarrheal episodes.
For individuals with irritable bowel syndrome (IBS), LGG has shown potential in alleviating symptoms. Studies indicate that it can reduce the frequency and severity of abdominal pain in children with IBS, an effect that may persist even after treatment cessation. This benefit is thought to be partly due to LGG’s ability to improve gut barrier function.
LGG also provides support for the immune system. It can reduce the incidence of respiratory tract infections, particularly in children attending daycare centers. This immune modulation is achieved through interactions with immune cells and by promoting a balanced immune response.
Regarding allergy management, LGG has been studied for its role in reducing the risk and severity of atopic dermatitis. Probiotic supplementation, including LGG, can accelerate the maturation of the immune system and improve the gut microbiome, which can lead to better management of symptoms. LGG contributes to enhancing gut barrier function and promoting immune response development in infants with atopic dermatitis.
Finding and Using LGG Probiotic
LGG is most commonly found in dietary supplements, where it is concentrated and standardized for consistent delivery. These supplements are available in various forms, such as capsules, powders, or chewable tablets. While LGG is widely available in supplement form, some fermented foods, such as certain yogurts and dairy products, may also contain this beneficial bacterium.
When using LGG probiotic supplements, follow the instructions on the product label. For general health, a typical daily dose is one capsule. Daily doses often range from 1 to 10 billion colony-forming units (CFU). It is advised to take probiotic supplements a few hours after any antibiotics to maximize their effectiveness.
Important Considerations for LGG Probiotic Use
While LGG probiotics are generally considered safe for most healthy individuals, some mild side effects can occur. These may include temporary digestive discomforts such as increased stomach gas or bloating. These symptoms typically subside as the body adjusts to the new bacteria.
Certain groups should exercise caution or consult a healthcare professional before using LGG. Individuals with a weakened immune system or short bowel syndrome may be at a higher risk for adverse events, including infections. Professional advice is recommended for those with underlying health conditions or specific health concerns.