Is There a Test for RSV? When and How to Get Tested

Respiratory Syncytial Virus (RSV) is a common respiratory virus that infects the lungs and breathing passages. While many experience mild, cold-like symptoms, RSV can cause serious infections, especially in vulnerable populations. Understanding when RSV testing is available and beneficial helps individuals make informed health decisions.

How RSV is Diagnosed

Diagnosing RSV typically involves collecting a sample from the respiratory tract, most commonly from the nose. One frequent method is a nasopharyngeal aspirate or wash, where a saline solution is inserted into the nose and gently suctioned out to collect mucus. Alternatively, a nasal swab can be used, involving a soft swab inserted into the nostril to collect a sample from the nasal passages. The collected sample is then sent for laboratory analysis.

Two primary types of tests are used to detect RSV: rapid antigen tests and molecular tests. Rapid antigen tests identify specific viral proteins, known as antigens, in the nasal sample and can provide results quickly, often within an hour. While convenient, these tests may have lower sensitivity, particularly in older children and adults who tend to have lower viral loads. Molecular tests, such as real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assays, detect the virus’s genetic material. These PCR tests are more sensitive and accurate, though results may take longer as samples are often sent to a laboratory.

When to Seek RSV Testing

Most healthy adults and older children with RSV will experience mild symptoms, similar to a common cold, and typically recover within one to two weeks without needing specific testing. However, testing becomes more relevant for individuals at higher risk for severe illness. These include infants (especially under six months), young children, older adults (particularly those over 65), and individuals with underlying health conditions like chronic lung or heart disease or weakened immune systems. In these groups, RSV can lead to more severe complications such as bronchiolitis or pneumonia.

Symptoms that might prompt testing in these vulnerable populations include wheezing, a severe cough, rapid or troubled breathing, or a bluish discoloration of the skin. For infants under six weeks, significant symptoms like difficulty breathing may warrant testing due to a heightened risk for apnea. Testing is generally most effective when performed early in the course of the illness, ideally within the first few days of symptom onset, as the amount of virus in the body decreases over time. While testing can confirm an RSV infection, the decision to test often depends on whether the result will influence treatment or infection control measures for at-risk individuals.

Interpreting RSV Test Results

An RSV test result will be either positive or negative. A positive result indicates RSV was detected in the sample. For most individuals, a positive RSV diagnosis means management focuses on supportive care, such as staying hydrated and managing symptoms, as there is no specific antiviral treatment. In some cases, particularly for infants, young children, or older adults with severe symptoms, a positive result might lead to hospitalization for supportive care like oxygen therapy or intravenous fluids.

A negative RSV test result means the virus was not detected in the collected sample. However, a negative result does not completely rule out an RSV infection. This can occur if the test was conducted too early or too late in the infection when the viral load was low, or if the sample was not collected adequately. If symptoms persist or are severe and consistent with RSV, healthcare providers may consider other diagnoses, conduct additional tests for other respiratory viruses, or continue to manage symptoms based on clinical judgment.