Is Mycoprotein Healthy? Benefits and Side Effects

Mycoprotein is one of the more nutritionally impressive meat alternatives available. With 11 grams of protein and 6 grams of fiber per 100 grams, only 85 calories, and almost no saturated fat, it checks most of the boxes you’d want from a protein source. But the benefits go beyond the nutrition label: clinical trials show meaningful effects on cholesterol, blood sugar, appetite, and even muscle building.

Nutritional Profile at a Glance

Mycoprotein is made from a naturally occurring fungus that’s fermented in vats, then processed into a fibrous texture that mimics meat. Per 100 grams (wet weight), it delivers 11 grams of protein and 6 grams of dietary fiber while containing just 2.9 grams of total fat, only 0.7 grams of which is saturated. It has zero cholesterol and a low 5 milligrams of sodium in its unprocessed form. It’s also a solid source of zinc (9 mg per 100 g) and selenium (20 μg per 100 g).

One notable gap: mycoprotein contains no vitamin B12. If you’re replacing meat with mycoprotein as a primary protein source, you’ll need B12 from fortified foods or supplements. Iron content is also modest at 0.5 mg per 100 grams, which is lower than most red meat or legumes.

Protein Quality and Muscle Building

Mycoprotein scores a 0.89 on the PDCAAS scale, which measures how well your body can use the protein. For context, a perfect score is 1.0 (most animal proteins), so mycoprotein lands well above typical plant proteins like beans and grains. By dry weight, it’s roughly 45% protein.

What’s more surprising is how it performs for muscle growth. A study in resistance-trained young men compared mycoprotein to milk protein, matching both for leucine content (the amino acid that triggers muscle repair). Mycoprotein stimulated muscle protein synthesis at roughly double the rate of milk protein, both at rest and after exercise. That’s a striking result, since dairy protein is typically considered the gold standard for post-workout recovery. The researchers speculated that mycoprotein’s unique fiber and nutrient matrix may slow digestion in a way that sustains amino acid delivery to muscles over a longer period.

Effects on Cholesterol

Mycoprotein has a consistent track record in cholesterol research. In one clinical trial published in The American Journal of Clinical Nutrition, participants eating mycoprotein saw a 13% reduction in total plasma cholesterol, while the control group showed no change. LDL cholesterol, the type most associated with cardiovascular risk, dropped by 9% in the mycoprotein group while actually increasing by 12% in the control group.

The likely driver is the fiber. Two-thirds of mycoprotein’s fiber is beta-glucan, the same type of soluble fiber found in oats that’s well established as a cholesterol-lowering agent. The remaining third is chitin, a fiber found in crustacean shells and insect exoskeletons. A typical 75-gram serving of mycoprotein delivers about 4 grams of beta-glucan and 1.5 grams of chitin.

Blood Sugar Response

For people managing blood sugar, mycoprotein performs well compared to animal protein. In a randomized controlled trial involving people with type 2 diabetes, mycoprotein reduced the post-meal blood glucose response by 27% compared to chicken. The effect was comparable to soy protein, with no significant difference between the two. Importantly, insulin levels weren’t significantly different across the protein sources, meaning mycoprotein achieved the lower glucose response without forcing the body to produce extra insulin.

This likely comes down to mycoprotein’s fiber content slowing the absorption of carbohydrates eaten alongside it, keeping blood sugar from spiking as sharply after a meal.

Appetite and Weight Management

Mycoprotein is unusually filling for its calorie count. In a trial with overweight and obese adults, eating a high-mycoprotein meal led to 10% fewer calories consumed at the next meal compared to eating the same amount of chicken. That translated to about 67 fewer calories at lunch. Over the full 24 hours, participants who ate mycoprotein consumed roughly 188 fewer calories (9% less) than those who ate chicken.

The interesting part is that the researchers couldn’t pin the effect on the usual appetite hormones. Levels of GLP-1 and PYY, two gut hormones that typically signal fullness, were no different between the mycoprotein and chicken meals. The satiating effect may instead come from the physical bulk and fibrous texture of mycoprotein, which could slow stomach emptying mechanically rather than hormonally.

Fiber and Gut Health

Six grams of fiber per 100 grams is high for any protein source. Most meats contain zero fiber, and even legumes only reach similar levels once you account for their much higher calorie and carbohydrate content. The fiber in mycoprotein is a combination of beta-glucan (about two-thirds) and chitin (about one-third). Both are fermented by gut bacteria into short-chain fatty acids, which fuel the cells lining your colon and play a role in reducing inflammation throughout the body.

One practical advantage of mycoprotein over legumes: it appears to contain minimal anti-nutritional factors like phytates and oxalates. Soybeans, for comparison, contain between 82 and 285 mg of oxalates and up to 2.2 grams of phytates per 100 grams of dry seed. These compounds can reduce mineral absorption. Mycoprotein’s fermentation-based production process largely avoids these issues, which may explain why its zinc and selenium are relatively bioavailable.

What Changes in Commercial Products

Raw mycoprotein and the products you buy in stores are not the same thing. Commercial mycoprotein products (the most well-known brand is Quorn) typically add binding agents and flavorings that change the nutritional picture. Depending on the product, you might find egg white, soy protein isolate, carrageenan, phosphates, and added salt. Some Quorn products use egg albumin as a binder, which makes them unsuitable for vegans, though the company also makes vegan-friendly lines using potato protein instead.

Sodium is the biggest shift. While raw mycoprotein contains just 5 mg of sodium per 100 grams, processed products like nuggets, fillets, and sausages can contain significantly more due to added salt and flavoring. Checking the label matters, especially if you’re watching sodium intake. The core mycoprotein inside those products retains its nutritional benefits, but the overall package depends on what else goes in.

Allergic Reactions

Because mycoprotein comes from a fungus (Fusarium venenatum), people with mold sensitivities or mushroom allergies should approach it cautiously. Allergic reactions to mycoprotein do occur, though they’re uncommon. Symptoms can range from mild gastrointestinal discomfort, including nausea and bloating, to more serious reactions like hives or, in rare cases, anaphylaxis. If you have known allergies to fungi or molds, starting with a small portion and monitoring your response is a reasonable approach. Some people also experience digestive adjustment when first eating mycoprotein regularly, likely because of the chitin fiber, which most Western diets don’t include in significant amounts.