Is Left Posterior Fascicular Block Dangerous?

A diagnosis of Left Posterior Fascicular Block (LPFB) often raises questions about its implications for heart health. This condition involves a specific part of the heart’s electrical wiring. Understanding how it functions, how it is identified, and what it may signify is important.

Understanding Your Heart’s Electrical System

The heart’s ability to pump blood relies on a precisely coordinated electrical system. This system generates and transmits electrical signals that tell the heart muscle when to contract. The process begins in the sinoatrial (SA) node, the heart’s natural pacemaker, located in the upper right chamber.

The electrical impulse spreads from the SA node across the upper chambers, causing them to contract. The signal then travels to the atrioventricular (AV) node, where it is momentarily delayed, allowing the upper chambers to fully empty blood into the lower chambers. From the AV node, the impulse moves into the bundle of His, which then divides into the right and left bundle branches. These branches further subdivide into a network of Purkinje fibers, which rapidly distribute the electrical signal throughout the muscular walls of the lower chambers, prompting their contraction and pumping blood to the lungs and body.

What is Left Posterior Fascicular Block?

Left Posterior Fascicular Block (LPFB) is a disruption or delay in the electrical signal pathway within the left posterior fascicle. This fascicle is one of the two main divisions of the left bundle branch, responsible for delivering electrical impulses to the posterior and inferior walls of the left ventricle. When this pathway is affected, the electrical signals are delayed or blocked from reaching that specific part of the heart.

As a result, other parts of the conduction system, primarily the left anterior fascicle, must compensate by delivering the impulse to the affected area. This compensation means the left ventricle still receives the necessary electrical activation, but the sequence is altered and delayed. LPFB is considered an electrical conduction issue, meaning it affects how impulses travel, rather than being a structural problem with the heart muscle itself. This block can be partial or complete, and sometimes it may occur intermittently.

Is LPFB a Cause for Concern?

For many individuals, an isolated Left Posterior Fascicular Block (LPFB) often does not cause symptoms. It may not require specific treatment because the heart’s electrical system can usually find alternative routes to ensure effective left ventricle contraction. The prognosis for LPFB without any underlying heart disease is excellent, with no change in life expectancy.

However, LPFB can sometimes indicate an underlying heart condition. It is most commonly associated with heart damage from conditions such as coronary artery disease, which involves reduced blood flow to the heart due to narrowed arteries. Other associations include cardiomyopathy; high blood pressure; and aortic valve disease. LPFB can also occur in the context of a heart attack, particularly an inferior myocardial infarction.

Isolated LPFB is relatively uncommon because the posterior fascicle has a robust structure and a dual blood supply, making it less susceptible to damage compared to other parts of the conduction system. It is more frequently observed in conjunction with Right Bundle Branch Block (RBBB), a combination referred to as bifascicular block. When LPFB occurs alongside RBBB, especially in the setting of a heart attack, there is an increased risk of progression to a complete heart block, which is a more serious condition where the electrical signals are fully interrupted.

Diagnosis and Clinical Management

Left Posterior Fascicular Block is primarily diagnosed through an electrocardiogram (ECG or EKG). LPFB presents with specific patterns, including a right axis deviation, along with characteristic rS and qR complexes in certain leads. The QRS duration, which reflects the time it takes for the ventricles to depolarize, remains normal or only slightly prolonged in LPFB.

If LPFB is identified, healthcare providers may conduct further investigations to determine if there is an underlying cause, particularly if symptoms are present or risk factors exist. This evaluation may include laboratory tests to check cardiac enzymes or electrolyte levels, and an echocardiogram to assess the heart’s structure and function. Stress testing might also be considered if coronary artery disease is suspected.

The management approach for LPFB focuses on addressing any identified underlying heart conditions rather than treating the block itself. For example, if coronary artery disease is found, treatment might involve lifestyle changes, medications, or revascularization procedures. For asymptomatic individuals with isolated LPFB, ongoing monitoring with regular follow-up appointments and serial ECGs is recommended to observe for any changes or progression. Pacemaker implantation is not necessary for isolated LPFB, but it may be considered if LPFB is part of a more extensive conduction disorder, such as when it occurs with Right Bundle Branch Block and progresses to a complete heart block.