Is It Normal to Get Sick After a Tattoo?

Tattooing introduces foreign pigment into the dermis layer of the skin. This process triggers an acute inflammatory response as the immune system mobilizes to heal the wound and contain the ink particles. While the skin is being punctured repeatedly by a needle, feeling unwell afterward is a very common experience. It is important to know how to distinguish between the normal healing process and a developing complication that requires medical attention.

The Body’s Expected Response to Tattooing

A fresh tattoo is an open wound, and the body’s first reaction is to initiate the healing cascade, which can cause temporary, systemic symptoms often referred to as “tattoo flu.” This exhaustion is compounded by the stress of a long session and the pain endured during the process.

Localized side effects are an expected part of the inflammatory response in the first 24 to 48 hours. The tattooed area will exhibit mild to moderate swelling, redness, and tenderness, similar to a sunburn. Some individuals may experience transient chills or a slight temperature spike, typically below 100.4°F (38°C), as the immune system begins its work. These normal effects should begin to diminish consistently after the second day, signaling that the body is successfully managing the micro-wounds created by the needles.

Recognizing Signs of Infection and Allergic Reaction

Symptoms that worsen instead of improve after the initial 48 hours suggest a localized problem requiring professional intervention. A bacterial infection is often indicated by pain that intensifies, localized heat that radiates from the tattoo, or redness that spreads beyond the original boundaries. A clear sign of infection is the presence of thick, yellow, green, or foul-smelling discharge leaking from the tattoo site. Furthermore, a sustained or rising fever of 100.4°F (38°C) or higher signals that the infection is becoming more serious.

An allergic reaction presents differently, with red and yellow inks being common culprits. These reactions typically manifest as intense, persistent itching, especially if it does not subside after the first few days of healing. The skin may develop raised, hard bumps called granulomas, where immune cells have walled off the foreign pigment they cannot eliminate. Severe, non-subsiding swelling, flaking, or a rash that remains confined to the inked area also suggests an allergic response rather than a bacterial infection.

Serious Systemic Complications

While rare, a localized skin infection can progress into a life-threatening systemic illness if not addressed promptly. The greatest concern is the development of sepsis. Recognizing the signs of sepsis is time-sensitive and requires immediate emergency medical care.

Symptoms of a systemic infection include extreme shivering, confusion, a rapid heart rate, very low blood pressure, and difficulty breathing. These indicate the infection has overwhelmed the body’s defenses and is a medical emergency. Additionally, though it does not cause immediate acute sickness, receiving a tattoo from a non-sterile environment carries the low risk of transmitting bloodborne pathogens like Hepatitis B, Hepatitis C, or HIV.

Minimizing Risk Through Proper Aftercare

The most effective way to prevent complications is through strict adherence to proper aftercare instructions provided by the artist. Minor concerns, like dryness or mild irritation, can often be discussed with the tattoo artist, but any progressive symptoms of infection or severe allergic reactions must be evaluated by a physician immediately.

Aftercare Instructions

The healing process requires careful attention to prevent infection:

  • Hands must be washed thoroughly with soap before touching the new tattoo for any reason.
  • Cleaning should be performed two to three times daily using a mild, fragrance-free soap and lukewarm water, followed by patting the area dry with a clean paper towel.
  • A thin layer of a recommended ointment or fragrance-free lotion should be applied to keep the skin moisturized without suffocating the wound.
  • It is imperative to avoid soaking the tattoo in water, which means no swimming in pools, hot tubs, or natural bodies of water for at least two to four weeks.
  • The healing process can be disrupted by picking or scratching at scabs and peeling skin, which can introduce bacteria and lead to infection.