Is Deltamethrin Harmful to Humans?

Deltamethrin is a synthetic pyrethroid insecticide, a man-made version of natural insecticides found in chrysanthemum flowers. This chemical is highly effective against a wide range of insects, making it a popular choice for household pest control, agriculture, and the manufacture of long-lasting insecticidal mosquito nets. While Deltamethrin is designed to be highly toxic to insects, understanding its potential effects on human health is important. The potential for harm depends heavily on the concentration, the route of exposure, and the duration of contact.

How Deltamethrin Affects the Human Body

Deltamethrin exerts its effect by targeting the nervous system, classifying it as a neurotoxin. Specifically, it belongs to the Type II pyrethroids, which alter the function of voltage-gated sodium channels in nerve cell membranes. These sodium channels regulate the flow of sodium ions, which is essential for nerve signal transmission. The insecticide interferes with the normal closing mechanism of these channels, causing them to remain open for an extended period. This prolonged opening leads to an uncontrolled influx of sodium ions, resulting in the overstimulation and repetitive firing of nerve cells.

Mammals, including humans, are generally less susceptible to Deltamethrin’s effects compared to insects, primarily due to higher body temperature and the capacity to rapidly metabolize and excrete the chemical. However, significant exposure can still cause adverse effects by disrupting nervous system function. Deltamethrin is generally considered to have moderate to minimal acute toxicity orally and minimally irritating via the dermal route in its formulated products. The severity of the internal biological response is tied to the amount absorbed and the specific formulation. Exposure to high concentrations can cause systemic neurotoxicity.

Recognizing Signs of Exposure

Symptoms of Deltamethrin exposure are directly related to its action on the nervous system and the route by which it enters the body. Dermal exposure typically results in localized skin sensations. This is characterized by paresthesia, described as a transient tingling, itching, burning, or numbness, most often occurring on the face or other exposed skin areas. These localized skin effects are usually reversible and temporary, often resolving within hours to 48 hours. Inhalation of spray mist or dust can lead to respiratory irritation, with symptoms such as coughing, sneezing, and a burning sensation in the nose and throat.

Oral ingestion can lead to more serious systemic effects. Systemic symptoms can include dizziness, headache, fatigue, and blurred vision. Gastrointestinal issues like nausea, vomiting, and abdominal pain often occur shortly after ingestion. In severe poisoning, more serious signs of neurotoxicity can develop, such as muscle twitching (fasciculations), convulsions, and potentially loss of consciousness.

Safe Use and Exposure Prevention

The risks associated with Deltamethrin are significantly mitigated when the product is used strictly according to label instructions. Following the label is the primary defense against exposure and potential harm, including adhering to the recommended application rates and methods.

Wearing appropriate Personal Protective Equipment (PPE) is necessary when handling concentrated forms or during application. This typically involves chemical-resistant gloves, protective clothing, and eye protection to prevent skin and eye contact. If the product is applied as a spray or dust, a respirator or face mask should be used to avoid breathing in the mist or vapors.

Application areas must have adequate ventilation to prevent the buildup of airborne concentrations. Indoors, all food, utensils, and food preparation surfaces should be covered or removed before treatment. Children and pets must be restricted from treated areas until the application has completely dried or for the time specified on the product label. Containers should be tightly closed and stored in a cool, dry, and well-ventilated area, inaccessible to children and pets, and separated from food, drink, and animal feed to prevent accidental ingestion.

Medical Response to Deltamethrin Exposure

Immediate action is necessary following any suspected exposure. If Deltamethrin contacts the skin, the contaminated clothing must be removed immediately, and the affected area should be thoroughly washed with soap and plenty of water for at least 15 minutes. For eye exposure, the eye should be flushed gently with a steady stream of clean water for a minimum of 15 minutes, holding the eyelid open. If inhalation occurs, the exposed person must be moved immediately to fresh air.

In cases of ingestion or if severe symptoms such as convulsions, difficulty breathing, or loss of consciousness occur, emergency medical help should be called immediately. It is helpful to have the product label available for medical personnel. A Poison Control Center should be contacted for advice on first aid. Treatment for pyrethroid poisoning is primarily supportive, focusing on managing symptoms and maintaining normal body functions. Inducing vomiting should only be done if specifically advised by a doctor or Poison Control Center.