How Twins Are Studied to Determine the Impact of Nature

The debate over whether “nature”—our genetic inheritance—or “nurture”—our environmental experiences—shapes human traits is a long-standing question in science. Researchers employ specialized methods, primarily through studying twins, to empirically separate these two influences. The logic behind twin studies rests on a naturally occurring experiment: comparing individuals who share either all or half of their variable genetic material while typically sharing the same upbringing. By analyzing the differences and similarities between these two types of twin pairs for any given trait, scientists can estimate the relative contributions of genes versus environment. This approach provides a framework for understanding the factors that drive individual differences in intelligence, personality, and disease risk.

The Essential Difference Between Twin Types

The foundation of twin studies lies in the precise genetic distinction between the two types of twins. Monozygotic twins result when a single fertilized egg splits into two embryos early in development. They are genetically identical, sharing virtually 100% of their DNA.

Dizygotic twins form when two separate eggs are fertilized by two different sperm during the same cycle. They are no more genetically similar than non-twin siblings, sharing about 50% of their variable genetic material. Crucially, both types of twins are usually raised in the same home by the same parents, sharing a common family environment to a similar degree. This disparity in genetic overlap, with the environment held relatively constant, creates the ideal scenario for comparison.

Designing the Core Twin Study

The standard methodology involves measuring a specific trait across a large sample of both monozygotic and dizygotic twin pairs. Researchers calculate a measure of similarity, often called a correlation rate, for the trait within each twin pair type. For example, they compare the correlation in height or political attitudes between monozygotic pairs to the correlation found in dizygotic pairs.

The core principle is that if a trait is heavily influenced by genes, monozygotic twins should be significantly more similar than dizygotic twins. Conversely, if a trait is primarily determined by the shared home environment, both types of twins would show a similarly high degree of correlation. If the trait is influenced by non-shared factors, such as different teachers or friend groups, the correlation will be lower for both twin types. Observing this pattern allows researchers to isolate the genetic influence.

Quantifying Influence: Heritability and Environment

The observed differences in trait correlation are translated into quantifiable measures using statistical modeling, often referred to as the ACE model. This model partitions the total variation observed in a trait within a population into three distinct components:

  • Heritability (A): The proportion of trait variation in the population attributable to genetic differences.
  • Shared Environment (C): Non-genetic influences that make family members more similar, such as parental socioeconomic status and general parenting style.
  • Non-Shared Environment (E): Unique, non-genetic experiences that make individuals different, including unique life events, differing peer groups, and measurement error.

By comparing the higher correlation in monozygotic twins to the lower correlation in dizygotic twins, researchers statistically estimate the size of the genetic (A) component, and subsequently estimate the influence of the shared (C) and non-shared (E) environmental components on the trait.

When Environment is Controlled: Twins Reared Apart

A variation of the twin study design involves studying monozygotic twins who were separated early in life and reared apart (MZA). These rare cases offer a direct way to estimate genetic influence, as the genetic material is identical but the shared family environment is completely removed.

If a high correlation for a trait is found between MZA twins, that similarity is attributed almost entirely to their shared genetics. Studies involving MZA twins show that for many psychological traits, such as personality and intelligence, similarities between twins reared apart are nearly as high as those reared together. This finding highlights the influence of genetic factors independent of the home environment.