How to Treat Stomatitis: Causes, Relief, and Prevention

Stomatitis refers to the general inflammation and soreness of the mucous membrane lining the mouth and lips. This condition can severely impact a person’s ability to eat, speak, and sleep due to the discomfort it causes. Stomatitis is not a single disease but a symptom of various underlying issues, ranging from physical trauma to systemic infections. Effective management relies on accurately identifying the specific cause, as treatment for one type of irritation may be ineffective for another.

Identifying the Source of Stomatitis

Recognizing the specific trigger is important because the appearance of the sore often indicates its origin. The most common form is Aphthous Stomatitis, widely known as canker sores. These are non-contagious ulcers that appear as round or oval lesions with a yellow-gray center and a distinct red border. They typically form on soft tissues, such as the inner cheeks and tongue underside, often triggered by minor injury, stress, or nutritional deficiencies like low Vitamin B12 or iron.

Infectious stomatitis may be viral or fungal. Viral forms, such as those caused by the herpes simplex virus (herpetic stomatitis), present as clusters of small, painful, fluid-filled blisters on the gums or the hard palate. Fungal stomatitis, primarily caused by an overgrowth of Candida albicans (thrush), manifests as creamy white patches that reveal red, inflamed tissue underneath when wiped away.

Denture-related Stomatitis is another common irritant, appearing as chronic redness and inflammation confined to the area directly beneath a dental appliance. This condition is frequently linked to poor denture hygiene, wearing the appliance while sleeping, or an ill-fitting device causing constant mechanical irritation. The environment under the denture encourages the overgrowth of yeast, leading to persistent inflammation.

Immediate Relief and Home Management

For immediate comfort, non-prescription methods focus on reducing pain and protecting the inflamed tissue from further irritation. Rinsing the mouth with a warm saline solution helps cleanse the area and reduce inflammation. A baking soda rinse, combining one teaspoon of baking soda with half a cup of water, can also neutralize oral acids and soothe the painful lesions.

Adjusting your diet offers significant palliative care by eliminating aggravating factors. Temporarily avoid foods that are spicy, acidic (like citrus fruits and tomatoes), salty, or physically abrasive (such as chips or hard toast). Opting for soft, bland foods and cool liquids minimizes contact and irritation during mealtimes.

Over-the-counter topical treatments provide targeted relief by forming a protective barrier or numbing the area.

  • Protective pastes, such as those containing carboxymethylcellulose (like Orabase), shield the raw nerve endings from saliva and friction.
  • Topical anesthetics, such as gels and liquids containing benzocaine, offer temporary pain relief by numbing the surface before eating or speaking.
  • Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, can be taken orally to help reduce overall mouth inflammation and manage pain.
  • Applying ice chips directly to the painful area can also provide a brief numbing effect and reduce localized swelling.

Professional Medical Treatments

When home care fails to provide adequate relief, a healthcare provider can prescribe targeted treatments based on the specific diagnosis. For severe or persistent aphthous ulcers, prescription-strength topical corticosteroids, such as fluocinonide or triamcinolone acetonide paste, are often the first line of treatment. These anti-inflammatory agents are applied directly to the lesion to accelerate healing and reduce swelling.

If the stomatitis is fungal, a physician will prescribe an antifungal medication to eliminate the yeast overgrowth. This typically involves a topical suspension, such as nystatin, or clotrimazole lozenges that dissolve slowly to deliver the medication directly to the affected tissues. For widespread or resistant infections, an oral antifungal tablet may be necessary.

Viral stomatitis, most commonly caused by the herpes simplex virus, is treated with antiviral medications. Drugs like acyclovir, valacyclovir, or famciclovir are most effective when started at the first sign of an outbreak, shortening the duration and severity of the blistering. In cases of severe ulceration, a short course of systemic corticosteroids, such as prednisone, may be prescribed to quickly control the inflammation.

Seek professional medical attention if symptoms are accompanied by a high fever, if pain makes it impossible to swallow liquids or maintain nutrition, or if lesions persist for longer than two weeks. These signs may indicate a more serious underlying infection or a systemic condition requiring a medical workup.

Preventing Recurrence

Long-term prevention focuses on managing chronic irritants and strengthening the body’s natural defenses. Maintaining rigorous oral hygiene is fundamental, involving gentle brushing with a soft-bristled toothbrush to avoid micro-trauma to the delicate mouth lining. Using a toothpaste that does not contain sodium lauryl sulfate (SLS) may help reduce the frequency of canker sore outbreaks for susceptible individuals.

Addressing systemic factors, particularly nutritional deficiencies, is a primary preventive strategy. Blood tests can identify low levels of iron, folate, or Vitamin B12, and supplementation can reduce the incidence of recurrent ulcers. Managing chronic stress and ensuring adequate rest are also recommended, as emotional and physical strain can compromise the immune system and trigger flare-ups.

Specific care is necessary for denture wearers to prevent chronic inflammation. Dentures should be cleaned thoroughly every day to remove microbial plaque and should be removed from the mouth for six to eight hours, ideally overnight, to allow the underlying tissues to rest and recover. Ensuring the denture fits properly is important, as mechanical rubbing from a loose appliance can cause trauma leading to stomatitis.