How to Treat and Prevent Blisters From Running

A blister on the foot is a common injury for runners, developing as a defense mechanism when repeated friction and shearing forces separate the skin layers. This separation allows plasma fluid to fill the resulting space beneath the outer layer of skin. Understanding the correct steps for immediate care and long-term prevention can significantly reduce time away from running and minimize the risk of complications.

Immediate First Aid for Blisters

Upon noticing a blister, carefully assess its size and pain level to guide the treatment strategy. If a blister is small and does not cause significant discomfort, it is best to leave the skin roof intact, as this provides a sterile, natural barrier against infection. The fluid inside will be reabsorbed by the body within a few days.

A large, taut, or painful blister, especially one located on a weight-bearing area, may require draining to relieve pressure and allow for activity. To do this safely, first wash the area and your hands thoroughly with soap and warm water. Sterilize a clean, sharp needle by wiping it with rubbing alcohol or heating it until red hot and allowing it to cool.

Gently puncture the blister at its edge in several spots, allowing the serous fluid to drain completely while taking care to leave the overlying skin intact. The remaining skin acts as a protective layer for the delicate tissue underneath, which is crucial for preventing infection. Once drained, gently pat the area dry and proceed with dressing the wound for protection.

Protecting and Dressing the Wound

Hydrocolloid bandages are a highly effective choice, as they contain gel-forming agents that absorb any remaining fluid and create a moist healing environment. This moist environment is preferred over a dry scab, as it can accelerate tissue regeneration and reduce pain. Hydrocolloid dressings are also waterproof and can often remain in place for several days.

To protect the blister from rubbing, a friction barrier can be created using padding like moleskin or adhesive felt. Cut a piece of moleskin larger than the blister, then fold it in half and cut a semi-circle out of the center to create a donut shape. This padding should completely surround the blister, lifting the shoe or sock material away from the injury without applying direct pressure to the damaged skin. Finally, cover the entire area with a non-stick gauze pad or tape to secure the padding and keep the wound clean.

Strategies for Preventing Future Blisters

Selecting the proper sock material is a simple yet effective strategy, as moisture-wicking fabrics like polyester or merino wool draw sweat away from the skin. Cotton socks should be avoided because they absorb moisture and remain wet, significantly increasing the risk of friction-related injury.

Shoe fit is equally important, and runners should ensure there is adequate space—about a thumb’s width—between the longest toe and the front of the shoe. Shoes that are too tight or too loose can cause movement that leads to hotspots. Anti-friction products, such as specialized balms, sticks, or petroleum jelly, can be applied to common friction points before a run to reduce rubbing.

Applying athletic tape or specialized blister tape directly to the skin acts as a second skin, preventing shear forces. This preventative taping should be applied smoothly over known hotspots before any rubbing occurs. Gradually increasing mileage allows the skin on the feet to naturally toughen and adapt to the repetitive stress of running.

Recognizing Signs of Infection

While most blisters heal without incident, monitor the wound for signs of bacterial infection. The skin surrounding the blister may become noticeably warmer to the touch, and the pain may intensify rather than subside after initial treatment.

The presence of pus, which is a thick, yellow or green discharge, indicates infection. Other concerning symptoms include spreading redness or red streaks radiating outward from the blister site. A systemic response, such as developing a fever or chills, indicates a serious infection that requires immediate medical consultation. Do not attempt to self-treat a blister if these symptoms appear, as professional medical attention is needed to prevent complications.