Abilify (aripiprazole) is an atypical antipsychotic medication prescribed for mental health conditions like schizophrenia, bipolar I disorder, and as an add-on treatment for major depressive disorder. An overdose happens when someone takes more than the recommended dose. Recognizing the signs and taking immediate action is important, as it can lead to severe health complications.
Recognizing an Overdose
An Abilify overdose can manifest through several physical and behavioral changes. Common symptoms include drowsiness, nausea, vomiting, and diarrhea. The person might also experience a rapid or irregular heartbeat, dilated pupils, and increased sensitivity to light.
More severe signs can involve weakness, fainting, or profound sedation. Some individuals may develop convulsions, seizures, shallow breathing, or enter a comatose state. Other neurological effects include muscle twitching, tremors, or dystonic reactions (involuntary muscle contractions). Lethargy can be notable, sometimes lasting for several days following an overdose.
What to Do Immediately
If an Abilify overdose is suspected, immediate action is necessary. Contact emergency services (911) or the Poison Helpline (1-800-222-1222) without delay. Providing accurate information about the medication and amount taken assists responders in preparing the appropriate medical response.
Remain with the person and keep them safe until medical help arrives. Do not attempt to induce vomiting, as this can be dangerous and is not recommended for medication overdoses. Instead, monitor their condition and provide relevant details to emergency personnel upon arrival.
Professional Medical Care
Upon arrival at a medical facility, professional care for an Abilify overdose focuses on supportive measures, as there is no specific antidote. Medical staff will monitor vital signs, including heart rate, blood pressure, and breathing. If ingestion occurred recently, gastric decontamination with activated charcoal might be performed to reduce medication absorption.
Intravenous fluids are often administered to maintain hydration and manage low blood pressure. Symptoms like extrapyramidal effects (movement disorders) can be managed with specific medications, such as diphenhydramine. Due to the medication’s long half-life (up to 75 hours for the parent compound and 95 hours for its active metabolite), extended observation in a medical setting is often necessary to monitor for delayed or prolonged effects. This ensures any re-emerging or persistent symptoms are promptly addressed.
Post-Overdose Recovery
Following medical stabilization, continued monitoring and follow-up care are important for recovery. Patients may experience lingering effects like prolonged lethargy or tremors for some time after the acute phase. Healthcare providers will assess for potential long-term complications and ensure the individual’s return to baseline health.
Addressing the underlying reasons for the overdose is a significant part of recovery. This may involve re-evaluating medication management strategies and providing ongoing mental health support. Connecting with mental health services can help prevent future incidents and support overall well-being.