Ondansetron orally disintegrating tablets (ODTs) are a specific form of medication primarily used to prevent and treat nausea and vomiting, often associated with treatments like chemotherapy, radiation therapy, or surgery. Unlike traditional pills, these tablets are designed to dissolve rapidly on the tongue without needing water. Understanding the correct administration of this unique dosage form is important to ensure its effectiveness.
Step-by-Step Administration
Administering an ondansetron ODT requires careful handling to maintain the tablet’s integrity. Ensure your hands are completely dry before touching the packaging. The tablet comes in a blister pack; peel back the foil backing gently rather than pushing the tablet through it. Pushing can damage the fragile tablet, making it difficult to administer correctly.
Once the foil is peeled back, carefully remove the tablet and immediately place it on top of your tongue. The ODT dissolves quickly upon contact with saliva. Allow the tablet to dissolve completely in your mouth.
After the tablet has fully dissolved, swallow it along with your saliva. Do not chew, crush, or swallow the tablet whole, as this can affect its intended rapid dissolution and absorption. If a tablet is accidentally dropped or damaged before administration, it should generally be discarded, and a new, intact tablet should be used.
Important Considerations When Taking
Water is generally not needed for administration, as ODTs dissolve with saliva. Attempting to take the ODT with water may increase the chance of experiencing a headache.
Proper storage maintains stability and effectiveness. These tablets should be kept in their original foil packaging until just before use to protect them from moisture and light. Store the medication at room temperature, typically between 68°F to 77°F (20°C to 25°C), and avoid humid environments or excessive heat or freezing temperatures. Heat and dampness can compromise the tablet’s integrity and reduce its efficacy.
If a dose is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Never take a double dose to make up for a missed one.
You should contact a healthcare provider if you experience any unexpected or concerning reactions after taking ondansetron ODT. This includes symptoms such as a rash, itching, swelling of the face or throat, trouble breathing, or changes in heart rhythm. Seeking medical advice is also recommended if you have questions about administration issues or experience severe abdominal pain or other serious side effects.