How to Protect Yourself From Syphilis

Syphilis is a bacterial sexually transmitted infection (STI) caused by the organism Treponema pallidum. While highly treatable with antibiotics, particularly in its early stages, the infection can lead to severe, long-term health complications if left undiagnosed. Prevention relies on understanding transmission methods and consistently implementing a layered approach to risk reduction.

Behavioral Strategies for Risk Reduction

The fundamental choice for eliminating the risk of syphilis transmission is to abstain from sexual contact entirely. Abstinence is the only method that offers 100% effectiveness against the spread of any sexually transmitted infection. For individuals who choose to be sexually active, reducing the number of partners significantly lowers the overall chance of exposure.

Another highly effective strategy is establishing a long-term, mutually monogamous relationship with a partner who has been tested and confirmed to be uninfected. Maintaining open and honest communication about STI status is a foundational part of this protective approach.

Effective Use of Barrier Methods

Barrier methods create a physical block that prevents the exchange of bodily fluids and direct contact with infectious sores. Male latex or polyurethane condoms are a highly recommended tool for reducing the risk of transmission during vaginal and anal intercourse. For oral sex, a condom or a dental dam should be used consistently to cover the contact area.

Correct and consistent application is necessary for these barriers to provide maximum protection. However, a syphilis sore, known as a chancre, can appear on areas not covered by a standard condom, such as the inner thighs or groin. Since transmission occurs through contact with these sores, barrier methods offer strong, but not absolute, protection.

The Role of Screening and Early Detection

Testing is a cornerstone of protection, as syphilis is often asymptomatic in its early stages. The initial infection may present with only a painless chancre that disappears on its own, making the infection easy to miss. Without screening, the disease can progress silently to later stages, where it can cause severe damage to the brain, nerves, and heart.

Individuals at increased risk, such as pregnant people, men who have sex with men, and those with multiple partners, should be tested regularly. For those with the highest risk factors, screening may be recommended as frequently as every three to six months. A simple blood test detects the antibodies produced in response to the Treponema pallidum bacteria.

If a diagnosis is confirmed, immediate treatment is administered with penicillin, which remains the standard therapy for all stages. This prompt intervention cures the infection, prevents progression, and stops the ability to transmit the disease. Currently, no vaccine exists, making behavioral strategies and routine testing the only effective means of protection.

Preventing Transmission Beyond Sexual Contact

While sexual contact is the primary route of infection, two other specific transmission routes are important to understand. The first is vertical transmission, which occurs when a pregnant person passes the infection to their baby during gestation, resulting in congenital syphilis. This outcome is entirely preventable when the mother is screened and treated early in pregnancy.

Screening is recommended for all pregnant individuals at their first prenatal visit, and sometimes again in the third trimester and at delivery. Treating the infected mother with penicillin during pregnancy is highly effective, preventing severe and permanent health issues for the infant.

Syphilis cannot be transmitted through casual contact with surfaces like toilet seats or shared eating utensils. The bacteria dies quickly outside of the body, meaning transmission requires direct contact with an active sore or bodily fluids.