How to Prepare for a Platelet-Rich Plasma (PRP) Injection

Platelet-rich plasma (PRP) therapy uses components from your own blood to support tissue healing. It involves concentrating platelets, which contain growth factors, and injecting this plasma into areas needing repair. These growth factors stimulate the body’s natural healing processes. Proper preparation for a PRP injection is important for safety and to achieve desired outcomes.

Medical Guidelines Before Your PRP Injection

Before a PRP injection, discontinue certain medications that could interfere with treatment effectiveness or increase side effects. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and aspirin should be avoided for 5 to 10 days prior. These medications work by reducing inflammation, which is a necessary initial step in the body’s healing process that PRP aims to trigger. By inhibiting inflammation, NSAIDs can hinder the growth factors released by platelets, potentially making the PRP less effective.

Blood-thinning medications, including prescription anticoagulants like warfarin, dabigatran, rivaroxaban, and apixaban, or antiplatelet drugs like clopidogrel, must be discussed with your healthcare provider. These medications increase the risk of bleeding and bruising at the injection site. Your provider will assess if temporary cessation is safe, especially for heart conditions. Acetaminophen (Tylenol) is generally safe for pain relief before and after the procedure as it does not interfere with platelet function or inflammation.

Certain supplements with blood-thinning effects or those that influence platelet function should be stopped before PRP therapy. Fish oil, Vitamin E, Vitamin A, ginkgo biloba, garlic, flax oil, and cod liver oil are examples often recommended to be discontinued, typically for 3 days to 1 week prior to the injection. These supplements can increase the likelihood of bruising and bleeding. Always provide a complete list of all medications, supplements, and herbal remedies to your healthcare provider for a personalized preparation plan.

Avoid alcohol consumption. Refrain from alcohol for 3 to 7 days before your PRP injection. Alcohol can thin the blood, increase the risk of bruising, and may negatively impact platelet function, which could reduce the effectiveness of the treatment. Smoking cessation is also recommended in the days or weeks leading up to the procedure. Smoking can impair circulation and the body’s healing capacity, which may compromise the outcomes of PRP therapy.

Lifestyle Adjustments in the Days Leading Up to PRP

Adjusting your lifestyle before a PRP injection supports optimal healing. Staying well-hydrated is important. Drinking plenty of water, often 8 to 10 glasses per day, can make the blood draw process easier and enhance plasma quality.

Focus on a healthy, balanced diet. Consume antioxidant-rich fruits and vegetables, lean proteins, and omega-3 fatty acids. Avoid processed foods, refined sugars, and inflammatory foods to reduce systemic inflammation. This nutritional approach supports the body’s natural healing mechanisms, creating a more favorable environment for PRP to work effectively.

Limit strenuous physical activity or any activities that might strain the treatment area. Avoid intense exercise for 24 to 48 hours before the procedure to prevent undue stress. This allows the body to conserve energy and resources, which can then be directed towards the healing process initiated by the PRP. Getting sufficient rest and quality sleep before your injection is equally important. Adequate sleep supports the body’s natural restorative functions, which are beneficial for recovery.

Practical Preparations for the Day of Your Injection

On the day of your PRP injection, practical steps ensure a smooth experience. Wear comfortable, loose-fitting clothing that allows easy access to the treatment area and the arm for blood draw. If your treatment area affects your ability to drive safely, or if sedation is involved, arrange for someone to drive you home.

Prepare a list of questions or any last-minute concerns for your healthcare provider to ensure you receive all necessary information and understand post-procedure expectations. Bring important items like your identification, insurance information, and any pre-filled forms the clinic may have provided.

Upon arrival at the clinic, you can expect a streamlined process. A medical assistant will likely take your blood pressure and review your medical history. Blood will be drawn, typically from your arm, and then processed in a centrifuge to separate and concentrate the platelets. The concentrated platelet-rich plasma is then prepared for injection, often with imaging guidance to ensure precise placement.