How to Kill MRSA: Treatment, Cleaning, and Prevention

Methicillin-resistant Staphylococcus aureus (MRSA) is a common type of bacteria that has developed resistance to several standard antibiotics. This resistance makes MRSA infections significantly harder to treat compared to typical staph infections. The bacterium is highly transmissible, spreading through direct skin contact, contaminated surfaces, and infected wounds. Understanding how to eliminate an active infection, sanitize the environment, and prevent future spread is crucial for public health and personal safety. This article details the clinical protocols used to treat active MRSA infections and the practical steps necessary for environmental control and prevention.

Medical Treatment Protocols for Active Infections

Eliminating an active MRSA infection requires a targeted medical strategy, often beginning with physical removal for localized infections. For skin and soft tissue infections presenting as abscesses or boils, the initial step is typically incision and drainage (I&D). This procedure physically removes the infected material and is often sufficient for uncomplicated infections without antibiotics. However, a healthcare provider must perform this procedure, as attempting to drain the infection at home can worsen the condition and spread the bacteria.

Antibiotic therapy is reserved for infections that are more severe, widespread, or show signs of systemic involvement like fever. The choice of antibiotic depends on the severity and location of the infection, guided by the specific sensitivity of the MRSA strain. For milder skin infections, oral antibiotics like trimethoprim-sulfamethoxazole (Bactrim), clindamycin, or doxycycline are prescribed, usually lasting 5 to 7 days.

Systemic infections, such as pneumonia or bloodstream infections, require more potent intravenous (IV) antibiotics. Vancomycin is a commonly used IV treatment for severe MRSA infections, requiring careful monitoring to prevent toxicity. Alternative IV options include daptomycin and linezolid.

It is important to complete the entire course of prescribed antibiotics, even if symptoms improve quickly. Stopping treatment prematurely increases the risk that the bacteria will survive and develop further resistance. Always consult a healthcare provider for proper diagnosis and the most effective treatment protocol.

Disinfecting Surfaces and the Home Environment

Contaminated surfaces and objects play a significant role in MRSA transmission, requiring specific protocols to eliminate the bacteria from the home. Focus on cleaning and disinfecting frequently touched surfaces and any items that have contacted an infected wound or bodily fluid, such as doorknobs, faucets, and bathroom fixtures.

For hard surfaces, use an Environmental Protection Agency (EPA)-registered disinfectant that claims effectiveness against Staphylococcus aureus or MRSA. Check the product label for the required contact time—the period the surface must remain visibly wet for the disinfectant to work. A fresh solution of household bleach, mixed at one tablespoon per quart of water, is also effective.

Laundry protocols must be adjusted for clothing, towels, and linens. Wash soiled items using regular detergent and the warmest water setting recommended for the fabric. Do not over-pack the machine to ensure thorough cleaning. Drying the laundry completely in a machine on a high heat setting is important, as air-drying may not be sufficient to eliminate the bacteria.

Proper disposal of contaminated dressings and bandages is essential. Used wound dressings should be promptly placed in a sealed plastic bag before being discarded with household trash. Items that cannot be effectively disinfected, such as disposable medical supplies, should be handled carefully to prevent indirect transmission.

Preventing Transmission Through Daily Personal Care

Preventing MRSA transmission relies heavily on consistent behavioral changes and specific personal care practices. Strict hand hygiene is the most important daily step, as MRSA spreads primarily through hand-to-hand contact. Hands should be washed frequently with soap and warm water for at least 20 seconds, especially after changing a dressing or touching an infected area. If soap and water are unavailable, use an alcohol-based hand sanitizer.

Proper wound management is a crucial component in preventing spread. Any cuts, scrapes, or active infections must be kept clean and completely covered with a fresh, dry bandage. The bandage acts as a barrier, containing infectious drainage. Dressings should be changed according to a healthcare provider’s instructions and disposed of immediately.

A healthcare provider may prescribe a decolonization protocol to eliminate MRSA carriage from the nose and skin folds. This regimen is aimed at individuals who carry the bacteria without an active infection but are at high risk of transmission. The protocol typically involves a five-day regimen using a topical antibiotic ointment (mupirocin) applied to the nostrils, combined with an antiseptic body wash containing chlorhexidine gluconate (CHG) used daily. Careful adherence is required to minimize the risk of resistance.

To further limit spread, personal items should never be shared:

  • Towels
  • Washcloths
  • Razors
  • Athletic gear