How to Get Rid of Canker Sores Overnight

Canker sores, medically known as aphthous ulcers, are small, shallow lesions that develop on the soft tissues inside your mouth or at the base of your gums. Unlike cold sores, these ulcers are not contagious and do not appear on the outer surface of the lips, but they can cause significant, acute pain that makes eating and speaking difficult. While completely eliminating a canker sore overnight is often unrealistic, you can employ targeted strategies to dramatically reduce pain and accelerate the healing process within a 24-hour window. The goal is to immediately numb the exposed nerve endings and then apply treatments that protect the sore while encouraging tissue regeneration.

Immediate Pain Relief Strategies

The most pressing concern when dealing with a canker sore is the intense discomfort caused by irritation to the exposed tissue. To quickly address this, seek out a topical anesthetic designed for oral use. These products, often available as gels or liquids, contain numbing agents like benzocaine (typically around 20%), which provides fast, temporary pain relief.

Apply a small amount of the anesthetic directly onto the ulcer using a clean cotton swab. The numbing effect begins almost instantly and can last for several hours, allowing you to eat or drink with greater comfort. Another simple method for acute pain management involves using cold therapy to temporarily dull the nerve sensation. Gently allowing a small piece of ice to dissolve over the canker sore provides a brief but effective reduction in both pain and surrounding inflammation.

Targeted Home and OTC Treatments for Healing

Once the immediate pain is managed, the next step is to introduce treatments that promote rapid healing and protection. A simple yet effective method is to use a baking soda rinse, which works by neutralizing the high acidity in the mouth that can irritate the ulcer. Create this solution by dissolving one teaspoon of baking soda in a half-cup of warm water and swishing it around the mouth. Alternatively, mix baking soda with water to form a thick paste and carefully dab it directly onto the sore to help dry out the lesion.

Another application for encouraging faster recovery is Milk of Magnesia, an antacid containing magnesium hydroxide. Applied directly, this product acts as an acid neutralizer, reducing irritation and pain by changing the local pH balance. Use a clean cotton swab to coat the sore with a thin film of the liquid, leaving it on for several minutes before gently rinsing your mouth. This application can be repeated multiple times throughout the day, especially after meals, to provide a protective layer.

Rinsing the mouth with a diluted hydrogen peroxide solution offers antiseptic properties that help clean the area and promote faster tissue repair. Mix a 3% hydrogen peroxide solution with an equal amount of water and apply this mixture directly to the sore with a cotton swab a couple of times daily. Over-the-counter canker sore covers or oral pastes also provide a physical barrier over the ulcer. These protective patches adhere to the sore, shielding it from friction caused by food or teeth, which allows the tissue underneath to heal more quickly.

Recognizing Severe Cases and When to See a Doctor

While most canker sores are minor and resolve with home care, certain signs indicate that a professional medical evaluation is necessary. Consult a doctor or dentist if the sore is unusually large (a major aphthous ulcer) or if the pain prevents you from eating or drinking adequately. These larger lesions are deeper than typical canker sores and may take several weeks to heal, sometimes leaving a scar.

Seek professional help if a canker sore persists for longer than two weeks, as most minor ulcers heal within 7 to 14 days. Sores that do not resolve within this timeframe, or those that frequently recur, might suggest an underlying health issue. Furthermore, if your canker sore is accompanied by systemic symptoms such as a high fever, diarrhea, a skin rash, or swollen lymph nodes, contact a healthcare provider immediately.