How to Cure a Hangover: What Works and What Doesn’t

You can’t cure a hangover instantly, but you can shorten it and blunt the worst symptoms with a combination of rehydration, sleep, food, and the right pain reliever. Most hangovers last about 18 hours from your last drink, or roughly 12 hours from when you wake up, with the majority resolving somewhere between 14 and 23 hours total. Understanding what’s actually happening in your body makes it easier to pick strategies that work and avoid ones that backfire.

Why Hangovers Happen in the First Place

A hangover isn’t just dehydration, though that’s part of it. When your liver breaks down alcohol, it produces byproducts that trigger inflammation throughout your body. Levels of inflammatory molecules like IL-6 and TNF-alpha rise in your blood during and after drinking, and higher concentrations of these molecules are directly linked to worse hangover severity the next day.

Your liver also generates a flood of free radicals during alcohol metabolism. These unstable molecules damage cells and create compounds your immune system treats as foreign invaders, launching yet another wave of inflammation. So a hangover is essentially your body running a low-grade immune response while simultaneously dehydrated and sleep-deprived.

Alcohol also wrecks your sleep architecture. It may knock you out faster, but in the second half of the night it fragments your sleep, increasing the time you spend in the lightest, least restorative sleep stages. That’s why you can sleep eight hours after drinking and still feel foggy and exhausted. The fatigue and cognitive slowness you feel the next day are partly a sleep quality problem, not just an alcohol problem.

What Actually Helps Once You’re Hungover

Water and Electrolytes

Alcohol is a diuretic, so you’ve lost more fluid than usual. Drinking water helps, but adding electrolytes (sodium, potassium, magnesium) speeds rehydration because your intestines absorb water more efficiently when electrolytes are present. Sports drinks, coconut water, or an oral rehydration solution all work. Sipping steadily is better than chugging a liter at once, which can upset an already irritated stomach.

Food

Eating can feel unappealing, but your blood sugar is likely low and your stomach lining is inflamed. Bland, easy-to-digest foods like toast, rice, bananas, or eggs give your body fuel without adding more irritation. Eggs contain an amino acid that supports your liver’s detoxification pathways. Avoid greasy or highly acidic foods if your stomach is already churning.

Sleep

Since alcohol robbed you of quality sleep during the night, napping is one of the most effective recovery tools available. Even a 90-minute nap can help your brain cycle through the restorative sleep stages it missed. If you have the luxury of sleeping in or napping during the day, take it.

Choosing the Right Pain Reliever

For headaches and body aches, ibuprofen or aspirin are generally the safer choices over acetaminophen (Tylenol). Acetaminophen and alcohol are a risky combination for your liver. Alcohol depletes a protective molecule called glutathione that your liver needs to neutralize a toxic byproduct of acetaminophen. At the same time, regular drinking ramps up the liver enzymes that produce that toxic byproduct in the first place. The result is a double hit: more toxin produced, less ability to clear it. Ibuprofen can irritate the stomach lining, so take it with food.

What Doesn’t Work

“Hair of the dog,” or drinking more alcohol the next morning, delays your hangover rather than curing it. You’re simply reintroducing the substance your body is trying to clear, which pushes the recovery timeline further out. Coffee can help with alertness, but caffeine is also a diuretic and can worsen dehydration if you’re not drinking water alongside it. There’s no evidence that greasy breakfast foods “absorb” alcohol. The time for food to make a real difference in absorption was before and during drinking, not after.

How to Prevent (or Reduce) the Next One

Eat Before and During Drinking

Food in your stomach slows the rate at which alcohol reaches your small intestine, where most absorption happens. This gives your liver time to process alcohol at a more manageable pace instead of being overwhelmed all at once. The best pre-drinking meals include a mix of protein, fat, and carbohydrates. Fat slows gastric emptying the most, so something like a meal with avocado, chicken, and rice is a solid choice. Snacking while you drink extends this protective effect.

Choose Lower-Congener Drinks

Congeners are toxic byproducts of fermentation that vary dramatically by drink type. Bourbon contains roughly 37 times the congeners found in vodka. Dark spirits (bourbon, brandy, dark rum), red wine, and whiskey are all high-congener drinks. Lighter options like vodka, gin, and white wine produce fewer of these compounds. This doesn’t mean light-colored drinks are hangover-proof, but at equal amounts of alcohol, they tend to cause milder symptoms.

Alternate with Water

Matching every alcoholic drink with a glass of water does two things: it slows your overall drinking pace and counteracts the fluid loss from alcohol’s diuretic effect. This is one of the simplest and most effective prevention strategies. It won’t eliminate a hangover if you’re drinking heavily, but it meaningfully reduces severity.

Pace Yourself

Your liver processes roughly one standard drink per hour. Every drink beyond that creates a backlog that generates more inflammatory byproducts and oxidative stress. Hangover severity tracks closely with how high that backlog gets. Spacing your drinks out and setting a limit before you start are more effective than any supplement.

Supplements and Natural Remedies

A few natural compounds show modest evidence for hangover relief, though none are miracle cures. Red ginseng has been shown in a small crossover study to reduce plasma alcohol levels and improve hangover severity scores in healthy men. The effect was real but not dramatic.

Dihydromyricetin (DHM), a flavonoid extracted from the Japanese raisin tree, has generated interest because of its effects on brain receptors that alcohol targets. In lab and animal studies, DHM counteracted alcohol’s effects on GABA receptors, which are a major site where alcohol acts in the brain. However, its ability to actually lower blood alcohol levels was weak. At higher alcohol doses, DHM didn’t significantly change how much alcohol was in the blood or how long it stayed there. It appeared to reduce intoxication-related behavior through brain receptor activity rather than by speeding up alcohol clearance. Human evidence is still limited.

Ginger can help with hangover-related nausea specifically, since it’s a well-established anti-nausea remedy. Peppermint tea works similarly for settling the stomach. Neither addresses the underlying inflammation, but if nausea is your primary complaint, they’re worth trying.

The Realistic Timeline

Hangover symptoms begin as your blood alcohol concentration drops toward zero, which is why you often feel fine at 2 a.m. but terrible at 8 a.m. From the time you wake up, expect roughly 12 hours before you feel fully normal, though this varies with how much you drank, your body size, and your individual metabolism. Some people bounce back in 8 hours; others feel off for a full day.

The most miserable window is typically the first few hours after waking. Nausea, headache, and sensitivity to light tend to peak early, while fatigue and brain fog linger longer. Front-loading your recovery (hydrating, eating something small, and taking a pain reliever with food as soon as you’re awake) can compress that miserable window and make the back half of the day much more tolerable.