How Long Does Swelling Last After Mohs Surgery on Face?

Mohs micrographic surgery is a precise method for removing skin cancer, particularly on the face, where preserving healthy tissue is a major concern. The technique involves removing thin layers of cancerous tissue one at a time and immediately examining them under a microscope until only cancer-free tissue remains. Because the face is rich in blood vessels and delicate structures, swelling (edema) is an expected part of the body’s natural inflammatory response to the tissue manipulation involved in the procedure. This post-operative puffiness is temporary and signals that the healing process has begun.

Expected Swelling Timeline

Swelling typically occurs almost immediately after the procedure. Edema becomes most visible within the first 24 to 48 hours following surgery. The intensity can be dramatic, especially if the surgery was performed near the eyes, nose, or forehead. Swelling commonly reaches its peak severity around 48 to 72 hours after the operation.

After reaching its maximum point, the most noticeable swelling begins to subside gradually over the next few days. Patients report a perceptible reduction in puffiness by the end of the first week post-surgery. While the bulk of the inflammation resolves quickly, minor residual puffiness can persist. Visible swelling typically resolves within two to four weeks, though slight firmness or flattening of the wound may continue for a few months as the scar matures.

Factors Influencing Swelling Severity

The duration and intensity of post-operative edema are influenced by the location of the surgery on the face. Areas with thinner skin and less underlying tissue, such as the eyelids, lips, and nasal tip, often swell more dramatically than thicker areas like the forehead or cheeks. Swelling around the eyes can be severe enough to temporarily obstruct vision due to fluid migration from nearby surgical sites.

The size and depth of the surgical defect directly correlate with the degree of tissue trauma and subsequent swelling. Larger defects require more extensive repair, which can lead to more prolonged localized edema. The chosen method of wound closure also plays a role; complex reconstructions, such as skin grafts or local tissue flaps, often result in more extensive or lasting swelling than a simple linear closure. Patient-specific health factors, including existing medical conditions or the use of certain medications, can affect the body’s inflammatory response and healing capacity.

Strategies for Reducing Edema

Maintaining head elevation is one of the most effective strategies for minimizing facial swelling. Patients should sleep with their head propped up on several pillows, or in a recliner, for the first few nights to encourage fluid drainage away from the surgical site. This practice helps prevent fluid from pooling in the face overnight, which often exacerbates morning puffiness.

Cold compression, when used correctly, can significantly reduce inflammation and discomfort during the first 48 hours. A cold compress, such as an ice pack wrapped in a thin towel, should be applied gently to the area for 15 to 20 minutes at a time, several times daily. Avoid placing ice directly onto the wound or leaving it on for too long, as this can damage the healing tissue.

Patients should limit strenuous physical activity, heavy lifting, and excessive bending over for at least the first week after surgery. These actions increase blood pressure to the head and can worsen swelling or cause bleeding. Reducing sodium intake can also help minimize fluid retention. Acetaminophen is recommended for managing discomfort, but anti-inflammatory medications like ibuprofen should typically be avoided unless cleared by the surgeon, as they may increase the risk of bleeding.

Identifying Abnormal Swelling

While some swelling is expected, certain signs suggest a complication requiring immediate medical attention. Swelling that suddenly increases or worsens after the initial 72-hour peak should be reported to the surgical team, as this departs from the normal healing pattern of gradual improvement.

Other red flags include edema accompanied by intense heat, spreading redness, or pus-like drainage, which are signs of infection. Swelling that is rock-hard, dark purple, or associated with severe, unrelieved pain might indicate a hematoma (a collection of blood under the skin). Any swelling paired with a fever or chills should prompt an immediate call to the doctor.