Sermorelin, a growth hormone-releasing hormone (GHRH) analog, stimulates the body’s natural production of growth hormone. Proper storage and handling are essential for its effectiveness and to ensure it delivers its intended therapeutic benefits. This includes attention to temperature, light exposure, and other environmental factors.
Sermorelin Stability Outside Refrigeration
The stability of Sermorelin when unrefrigerated differs between its lyophilized (powder) form and its reconstituted (liquid) form. The dry, powdered form is more stable and can tolerate room temperature for a short period, such as during transit. Upon receipt, it should be refrigerated promptly to preserve its potency.
Once Sermorelin is reconstituted with bacteriostatic water, its stability outside of refrigeration becomes much more limited. Reconstituted Sermorelin can maintain its effectiveness at room temperature for up to 72 hours. After this period, its integrity can no longer be assured, and it should be discarded.
Factors Influencing Sermorelin Degradation
Sermorelin, a peptide, is susceptible to degradation when exposed to certain environmental conditions. Elevated temperatures can accelerate the breakdown of its delicate peptide structure, leading to a loss of therapeutic properties.
Exposure to light, especially direct sunlight, also contributes to degradation. Light energy can induce chemical changes within the peptide, compromising its molecular structure and reducing its biological activity. Similarly, exposure to air and oxygen can promote oxidative reactions that degrade the compound, rendering it less effective or inactive.
Consequences of Improper Sermorelin Storage
Improper storage, such as leaving Sermorelin unrefrigerated for extended periods, can lead to a loss of its potency. When the medication degrades, it becomes less effective at stimulating growth hormone production, meaning patients may not achieve desired therapeutic results. This reduction in efficacy can interrupt treatment progress and lead to wasted medication.
Degradation primarily results in a loss of therapeutic effect. Adhering to proper storage guidelines is essential to ensure the medication retains its intended action and delivers consistent outcomes.
Optimal Storage and Handling Practices
For optimal long-term preservation, Sermorelin in its lyophilized powder form should be stored in a refrigerator at 2-8°C (36-46°F). It should be kept in its original vial and protected from direct light, heat, and moisture. Freezing the dry powder form should be avoided as it can compromise efficacy.
Once Sermorelin is reconstituted, it must be continuously refrigerated within the same temperature range of 2-8°C (36-46°F). Reconstituted Sermorelin typically maintains its potency for up to 30 to 90 days when stored correctly. If the medication is accidentally left unrefrigerated for up to 72 hours, it may still be viable. However, if left out longer, or if there is any uncertainty, it should be discarded, and a healthcare provider should be consulted.