How Is an Ovarian Biopsy Performed and What to Expect

An ovarian biopsy is a medical procedure involving the removal of a small tissue sample from an ovary. This tissue is then examined under a microscope by a pathologist. Its primary purpose is to diagnose or rule out various ovarian conditions, such as abnormal cell growth or cancerous cells. While a key diagnostic tool, an ovarian biopsy is often performed as part of a larger surgical procedure rather than as a standalone test. This approach helps ensure comprehensive assessment and treatment, particularly when ovarian cancer is a concern.

Types of Ovarian Biopsy

Ovarian biopsies can be performed through several methods.

A common technique is the laparoscopic biopsy, a minimally invasive procedure. It involves making small incisions, two or three, in the abdomen through which a laparoscope (a thin tube with a camera) and surgical instruments are inserted. This allows the surgeon to visualize the ovaries and collect a tissue sample.

Another method is the open biopsy, also referred to as a laparotomy. This is a more extensive surgical procedure that requires a larger incision in the abdomen. A laparotomy provides the surgeon with a direct and broader view of the abdominal and pelvic organs, which is beneficial when a larger tissue sample is needed or if other surgical interventions are planned concurrently.

A less common approach is the transvaginal ultrasound-guided biopsy. In this method, a needle is precisely guided through the vaginal wall into the ovary using real-time ultrasound imaging. This technique is reserved for specific situations, such as when a patient cannot undergo more invasive surgery due to other medical conditions or advanced disease.

Preparing for Your Biopsy

Prior to the biopsy, your healthcare provider will discuss your medical history, allergies, and all current medications. This helps the medical team plan the procedure safely.

You will receive specific instructions regarding medication adjustments, particularly if you are taking blood thinners like aspirin or ibuprofen. It is often necessary to stop these medications several days before to minimize bleeding risk. You will also receive fasting instructions, requiring you to avoid eating or drinking for several hours before the biopsy.

Arranging for support on the day of the procedure is important, as you will likely receive anesthesia and cannot drive yourself home. A friend or family member should accompany you. Before the procedure, you will review and sign informed consent forms, confirming your understanding and agreement to proceed.

The Biopsy Procedure Explained

The ovarian biopsy procedure begins with anesthesia. General anesthesia is used for laparoscopic and open biopsies, while image-guided biopsies may utilize local anesthesia with sedation.

Once anesthesia has taken effect, the medical team will position you for the chosen biopsy method. For laparoscopic and open procedures, the abdominal area is prepared and draped. The surgeon then creates incisions: small, approximately 1 cm cuts for laparoscopy, or a larger incision for a laparotomy.

Visualization of the ovary is achieved through different means. A laparoscope, with a camera, is inserted through an incision for laparoscopic biopsies. In open surgery, the surgeon directly visualizes the ovary. Ultrasound or CT imaging guides the needle for transvaginal or image-guided biopsies.

Tissue collection follows, where a small sample is carefully removed from the ovary, often using specialized forceps or a guided needle. After the tissue sample is secured, instruments are withdrawn, and incisions are closed with sutures or staples. The collected tissue is then sent to a laboratory for detailed pathological examination.

After Your Biopsy: Recovery and Care

Following an ovarian biopsy, immediate care begins in the Post-Anesthesia Care Unit (PACU), where medical staff monitor your vital signs as you recover. You can expect some discomfort, including pain at incision sites, abdominal bloating, or shoulder pain, particularly after laparoscopic procedures due to gas used to inflate the abdomen. Mild bleeding or spotting is also common.

Your doctor will provide guidance on pain management, including prescribed medication or over-the-counter options. You are advised to avoid certain over-the-counter pain relievers, such as aspirin or other blood thinners, unless specifically instructed. Activity restrictions will be in place, including avoiding strenuous activities, heavy lifting, douching, and tampon use for a specified period, typically several weeks.

Wound care instructions will be provided to keep incision sites clean and dry. You may be encouraged to walk short distances soon after surgery to aid circulation and recovery. A follow-up appointment will be scheduled to discuss the biopsy results and any further steps in your care plan.

Understanding Potential Risks

An ovarian biopsy, like all medical interventions, carries potential risks. Bleeding is a common complication, and a blood transfusion may be necessary for significant blood loss.

Infection at the incision site or internally within the abdominal cavity is a risk. Report symptoms such as fever, increased pain, or redness around the wound to your healthcare provider. Although rare, unintended damage to nearby organs, such as the bowel, bladder, or major blood vessels, can occur during the biopsy.

Risks associated with anesthesia include allergic reactions. The formation of scar tissue at the surgical site is a possibility. Blood clots, particularly in the legs, can develop after surgery due to reduced mobility; early movement during recovery is important.