How Far Apart Should You Take Antibiotics and Probiotics?

Antibiotics are powerful medications designed to combat bacterial infections. While effective against harmful bacteria, they can also impact the beneficial microorganisms residing in the gut. Probiotics, conversely, are live beneficial microorganisms that can support gut health. Understanding how to effectively use these two is key to maintaining a healthy internal balance.

Understanding the Interaction Between Antibiotics and Probiotics

Antibiotics kill or inhibit infection-causing bacteria. This often extends to beneficial gut bacteria, disrupting the natural flora balance. This disruption can result in gastrointestinal side effects like diarrhea.

Introducing probiotics aims to replenish these beneficial bacteria, helping to restore balance. The primary reason for separating the intake of antibiotics and probiotics is to protect the live probiotic cultures. If taken too closely, the antibiotic can destroy the beneficial bacteria in the probiotic supplement, reducing its effectiveness.

The Recommended Time Gap

To maximize the benefits of probiotics while on antibiotics, a time separation is generally recommended. It is advisable to take probiotics at least two to three hours before or after an antibiotic dose. This time gap allows the antibiotic to be absorbed and begin its action, minimizing direct interaction with the live probiotic cultures. Starting probiotics on the same day as antibiotics and continuing throughout the antibiotic course is often suggested.

Selecting the Right Probiotic

Not all probiotics are equally effective when taken with antibiotics; strain specificity is important. Saccharomyces boulardii is a yeast-based probiotic that is not affected by antibacterial antibiotics, making it a suitable choice to take concurrently. Certain bacterial strains, such as Lactobacillus rhamnosus GG, Lactobacillus acidophilus Rosell-52, Lactobacillus rhamnosus Rosell-11, and Bifidobacterium lactis Lafti B94, have also shown resilience and benefit when used alongside antibiotics. These specific strains have been studied for their ability to survive the antibiotic environment and help mitigate side effects like antibiotic-associated diarrhea.

Optimizing Probiotic Use During and After Antibiotics

Beyond timing, several factors can optimize probiotic use. It is recommended to continue taking probiotics throughout antibiotic treatment and for several weeks afterward to help restore gut flora. Consistency in daily intake is important, as probiotics do not permanently colonize the gut and their benefits fade if stopped. While some probiotics can be taken on an empty stomach, others may benefit from being taken with food; check the product’s specific instructions.

Proper storage is also important to maintain the viability of live probiotic cultures. Many probiotic strains are sensitive to heat and humidity, often requiring refrigeration. However, some products are designed to be shelf-stable through processes like freeze-drying or specialized packaging. Always consult the product label for specific storage instructions. For personalized advice, it is best to consult a healthcare professional.