How Does Geraniol Kill Insects? Its Biological Mechanisms

Geraniol is a naturally occurring organic compound, a monoterpene alcohol, found in the essential oils of plants like geraniums, roses, and lemongrass. Known for its pleasant, rose-like scent, it is used in perfumes and fragrances. Beyond its aromatic qualities, geraniol has insecticidal and repellent properties, offering a plant-derived approach to pest management.

How Geraniol Disrupts Insect Biology

Geraniol primarily exerts its insecticidal effects through two main mechanisms: neurotoxicity and cuticle disruption. It interferes with the nervous systems of insects, leading to their immobilization and eventual death.

Geraniol impacts the insect nervous system by inhibiting acetylcholinesterase (AChE), an enzyme essential for nerve impulse transmission. It prevents the breakdown of acetylcholine, a neurotransmitter, causing its accumulation at nerve synapses. This overstimulates the insect’s nervous system, leading to paralysis and death.

Geraniol can also interact with gamma-aminobutyric acid (GABA) receptors, significant targets within the insect nervous system. This interaction contributes to its insecticidal action.

Geraniol also disrupts the insect’s outer layer, the cuticle. It penetrates the waxy exoskeleton, causing cellular damage. The cuticle is essential for preventing water loss in insects. By affecting this waxy layer, geraniol causes rapid desiccation.

Geraniol also has repellent properties. It excites insect receptors, interfering with their ability to detect host odors. This disruption of their olfactory systems helps deter pests.

Target Pests and Practical Applications

Geraniol is effective against a broad spectrum of common household and garden pests, including:
Mosquitoes
Flies
Ticks
Mites
Ants
Bed bugs
Cockroaches
Crickets
Fleas
Earwigs
Gnats
Moths

This natural compound is utilized in various pest control products. It is found in sprays, diffusers, and candles that release the volatile compound into the air. Geraniol is also incorporated into impregnated polymers, body gels, and pet shampoos for direct application against external parasites.

Geraniol’s effectiveness varies depending on its concentration, formulation, and the insect species targeted. It is versatile for both contact and repellent applications in pest management strategies.

Safety Profile and Environmental Impact

Geraniol has a favorable safety profile for humans and pets when used as directed. Regulatory bodies like the U.S. Environmental Protection Agency (EPA) and the U.S. Food and Drug Administration (FDA) classify geraniol as generally recognized as safe (GRAS). This classification reflects its low mammalian toxicity compared to many synthetic pesticides.

Concentrated forms of geraniol can cause mild skin or eye irritation in sensitive individuals. Some people may experience skin sensitization or contact dermatitis. Always follow product instructions carefully.

From an environmental perspective, geraniol is environmentally favorable due to its natural origin and biodegradability. It readily breaks down in air, soil, and water. This rapid degradation means geraniol does not persist in the environment. Geraniol also does not appear to harm bees, a beneficial pollinator.