How Does a Sneeze Work? The Biology Behind the Reflex

A sneeze represents a common, involuntary biological reflex that most people experience regularly. This sudden, forceful expulsion of air from the lungs through the nose and mouth serves as a universal protective mechanism. Understanding its biology reveals how it maintains respiratory health.

Common Sneeze Triggers

A sneeze initiates when irritants enter the nasal passages, stimulating nerve endings within the nose. Common allergens like pollen, dust mites, pet dander, and mold can trigger this response as the immune system identifies them as foreign substances. Environmental irritants such as dust, smoke, strong odors, perfumes, or chemical fumes also provoke sneezing by physically irritating the nasal membranes. Sudden changes in temperature, like moving from a warm room to cold air, can stimulate nasal nerves and induce a sneeze.

Some individuals experience a sneeze reflex when exposed to bright light, a phenomenon known as the photic sneeze reflex or Autosomal Dominant Compelling Helio-Ophthalmic Outburst (ACHOO) syndrome. This genetic trait affects an estimated 18-35% of the population and is often inherited. Spicy foods can also irritate nerve endings in the nasal lining, leading to a sneeze.

The Sneeze Reflex Explained

The physiological process of a sneeze begins when sensory nerves in the nasal passages detect an irritant, sending signals to the brainstem. This signal activates a specific “sneeze center” located in the medulla oblongata, a part of the brainstem. The brain then coordinates involuntary muscle contractions throughout the body.

Initially, a deep breath is taken, filling the lungs with air. Following this, the chest muscles tighten, and the diaphragm contracts, building pressure within the lungs. The glottis, or vocal cords, briefly close, and the soft palate and tongue adjust to partially close the passage to the mouth. This creates a high-pressure expulsion of air, mucus, and foreign particles through both the nose and mouth. The expelled air can reach speeds of up to 100 miles per hour.

The Health Benefits of Sneezing

Sneezing serves a protective mechanism for the respiratory system. It helps to clear the nasal passages of foreign particles, irritants, and allergens that have been inhaled. This forceful expulsion prevents these unwanted substances from traveling deeper into the respiratory tract and potentially reaching the lungs, where they could cause infection or inflammation.

The reflex also aids in removing pathogens, such as viruses and bacteria, maintaining clear airways. Researchers have suggested that sneezing helps “reset” the cilia, which are tiny hair-like structures lining the nasal passages responsible for moving mucus and trapped particles. Sneezing is an important part of the body’s natural defense system, promoting overall respiratory health.

Curiosities of the Sneeze

A common belief suggests that it is impossible to sneeze with one’s eyes open, as they involuntarily close during the reflex. While eyes shut due to an involuntary reflex, it is physically possible to keep them open, and doing so does not cause them to pop out. The muscles holding the eyeballs in place are strong enough to prevent displacement, even with the temporary increase in pressure.

The photic sneeze reflex is triggered by a change in light intensity rather than the light itself. The exact mechanism is not fully understood, but it is thought to involve a crossover of signals between the optic nerve and the trigeminal nerve.

Suppressing a sneeze is not recommended due to the internal pressure it creates. This trapped pressure, which can be 5 to 24 times greater than a normal sneeze, can lead to complications. These risks include ruptured eardrums, throat injuries, broken blood vessels in the eyes or nose, and in extreme cases, even rib fractures or the rupture of a brain aneurysm.