How Common Are Varicoceles and Who Is at Risk?

Varicoceles are a common vascular condition affecting the male anatomy. This enlargement of veins in the scrotum can sometimes interfere with normal testicular function. The condition generally develops during periods of rapid growth, such as puberty, and may progress over time. Understanding the prevalence and potential implications of varicoceles is important for men’s reproductive health.

Defining the Condition

A varicocele is an abnormal dilation of the veins within the spermatic cord, known as the pampiniform plexus. These veins drain oxygen-depleted blood from the testicles back toward the heart. The condition is similar to a varicose vein found in the legs, but located in the scrotum. This enlargement occurs when one-way valves inside the testicular veins malfunction, causing blood to flow backward and pool. On physical examination, a large varicocele can sometimes be felt as a soft mass above the testicle, often described as feeling like a “bag of worms.”

Understanding Prevalence and Risk Factors

Varicoceles affect approximately 15% of all men. The highest incidence occurs between the ages of 15 and 25, suggesting the condition primarily forms during puberty. The condition is significantly more common on the left side of the scrotum, occurring in about 90% of cases due to anatomical factors. The left testicular vein has a longer path and enters the left renal vein at a perpendicular angle, which increases hydrostatic pressure.

The presence of a varicocele is strongly associated with male infertility. Among men seeking evaluation for infertility, the prevalence rises dramatically to between 30% and 40%. This makes it a commonly identified cause of abnormal semen analysis and a correctable factor in male infertility.

Clinical Implications and Symptoms

Many men with a varicocele remain asymptomatic. When symptoms do occur, they involve a dull, aching pain or a feeling of heaviness in the scrotum. This discomfort is often worse later in the day, after prolonged standing or strenuous physical activity, and may be relieved by lying down.

The primary concern is the potential impact on testicular health and fertility. The pooling of blood in the enlarged veins makes it difficult to regulate the temperature of the testicles. This elevated scrotal temperature is thought to disrupt sperm production and function. Over time, this impaired environment can lead to testicular atrophy, a noticeable shrinkage of the affected testicle. Chronic congestion and poor blood flow may also contribute to oxidative stress, damaging sperm DNA and reducing sperm count and motility.

Management and Treatment Options

Diagnosis of a varicocele begins with a physical examination, often performed while the patient is both lying down and standing. The healthcare provider may use the Valsalva maneuver, asking the patient to bear down, which helps make the enlarged veins more prominent. The diagnosis is confirmed with a scrotal ultrasound, which visualizes the dilated veins and assesses blood flow.

Not all varicoceles require intervention, especially if the patient is asymptomatic or fertility is not a concern; observation may be recommended. Treatment is reserved for men experiencing pain, those with documented fertility issues, or adolescents showing delayed testicular development. The goal of treatment is to seal off the affected vein, redirecting blood flow through alternative veins.

Two primary interventional options exist: surgical ligation and percutaneous embolization. Surgical ligation, or varicocelectomy, involves a surgeon tying off the problematic veins, often using a microscopic technique. Varicocele embolization is a less invasive, non-surgical procedure performed by an interventional radiologist, involving a catheter and using coils or a sclerosant to create a blockage. Both approaches are effective at resolving the condition and may lead to improved semen parameters and fertility outcomes.