How Bad Is Stage 3 Kidney Failure? What You Should Know

Chronic kidney disease (CKD) describes a progressive condition where kidney function declines over time. Understanding the specific stage of CKD is important for managing the condition. This article focuses on Stage 3 kidney failure, providing clarity on its implications and management.

Understanding Stage 3 Kidney Failure

Stage 3 kidney failure indicates mild to moderate kidney damage, impacting the ability to filter waste and excess fluid from the blood. This stage is defined by an estimated glomerular filtration rate (eGFR) between 30 and 59 milliliters per minute per 1.73 square meters (mL/min/1.73 m2). The eGFR measures kidney filtering capacity, with lower numbers indicating reduced function.

This stage is categorized into two substages: Stage 3a (eGFR 45-59 mL/min/1.73 m2) and Stage 3b (eGFR 30-44 mL/min/1.73 m2). At this point, waste products can accumulate, potentially leading to various health issues. While kidney damage is generally not reversible, significant steps can slow further decline.

Recognizing Symptoms and Related Health Issues

Individuals with Stage 3 kidney failure may experience symptoms as waste products accumulate. Common symptoms include persistent fatigue and weakness, often due to anemia. Swelling (edema) may appear in the hands, feet, or ankles due to fluid retention. Changes in urination patterns, such as urinating more frequently (especially at night) or observing foamy or discolored urine, are also possible.

Additional symptoms can include dry, itchy skin, muscle cramps, and difficulty sleeping. Some individuals may also experience lower back pain.

Beyond these symptoms, impaired kidney function at Stage 3 can lead to other health complications. These include high blood pressure, anemia, and early signs of bone disease where calcium and phosphorus levels become imbalanced. An increased risk of cardiovascular disease is also associated with Stage 3 CKD.

Strategies for Managing Stage 3 Kidney Failure

Managing Stage 3 kidney failure involves lifestyle adjustments and medical interventions to preserve kidney function and address associated health issues.

Dietary modifications are often recommended, focusing on reducing sodium intake to control blood pressure and fluid retention. Depending on lab results, limiting phosphorus and potassium may also be advised to prevent imbalances affecting bone health and heart rhythm.

Maintaining a healthy weight, engaging in regular physical activity, and stopping smoking are important lifestyle changes that can help slow disease progression.

Medical management includes medications to control blood pressure, such as ACE inhibitors or ARBs, which can protect the kidneys. Medications for managing blood sugar in those with diabetes and cholesterol-lowering drugs like statins may also be prescribed.

Supplements for iron, calcium, and vitamin D might be necessary to address anemia and bone health issues. Regular monitoring by a healthcare professional, including blood and urine tests, is crucial to track kidney function and adjust treatment plans.

Outlook and Potential Progression

The long-term outlook for individuals with Stage 3 kidney failure is variable, yet often positive with appropriate management. While kidney damage is generally not reversible, progression to more advanced stages can often be slowed or halted. Many individuals with Stage 3 CKD can maintain stable kidney function for years, and some may even see improvement.

Factors influencing progression include consistent adherence to prescribed treatments and lifestyle changes. Effective control of underlying conditions like diabetes and high blood pressure significantly impacts the disease’s course. Lifestyle choices, such as maintaining a healthy diet and regular exercise, play a substantial role in preserving kidney health.

While progression to Stage 4 or 5 is possible, it is not a certainty. A large number of people with Stage 3 CKD will not advance to kidney failure requiring dialysis or transplant.