How an Ovarian Biopsy Is Done: The Different Methods

An ovarian biopsy is a medical procedure that obtains a small tissue sample from an ovary for detailed examination. It helps healthcare providers investigate ovarian abnormalities. The tissue is then analyzed by a pathologist to identify irregularities.

Understanding the Need for an Ovarian Biopsy

A doctor might recommend an ovarian biopsy to investigate various ovarian conditions. This includes evaluating suspicious masses or cysts discovered during imaging tests, such as ultrasounds or magnetic resonance imaging (MRI), which can suggest abnormal cell growth. The procedure is also performed to confirm a diagnosis of ovarian cancer or to determine its stage. In some instances, a biopsy helps differentiate between cancerous and non-cancerous growths. It can be crucial when other diagnostic methods are inconclusive or when planning treatment like neoadjuvant chemotherapy.

Different Approaches to Ovarian Biopsy

Several methods exist for performing an ovarian biopsy, with the choice depending on the specific situation and the nature of the ovarian finding. The type of anesthesia used also varies significantly among these methods.

Laparoscopic Biopsy

A laparoscopic ovarian biopsy is a minimally invasive surgical procedure that uses small incisions, typically a few small cuts in the lower abdomen. A thin tube with a camera, called a laparoscope, is inserted through one incision, allowing the surgeon to view the pelvic organs on a screen. Additional small instruments are then passed through other incisions to grasp the ovary and collect the tissue sample. This procedure is usually performed under general anesthesia. Patients can often go home the same day.

Open Biopsy (Laparotomy)

An open biopsy, also known as a laparotomy, is a more traditional and invasive surgical approach. During this procedure, the surgeon makes a larger incision in the abdomen to directly access the ovaries and surrounding areas. This method is often chosen when a larger tissue sample is needed or if there are concerns about extensive disease that requires broader exploration. Like laparoscopic procedures, a laparotomy is performed under general anesthesia. Recovery from a laparotomy is generally longer, with a full recovery potentially taking four to six weeks.

Image-Guided Biopsy

Image-guided biopsies use imaging technology, such as ultrasound or CT scans, to direct a needle to the precise location of the ovarian mass. This method is often used for accessible cysts or masses, or when a patient cannot undergo surgery due to other health conditions or advanced cancer. The needle is inserted through the skin, and the imaging helps the doctor guide it accurately to obtain a tissue sample. Local anesthesia is typically used, or conscious sedation may be administered. Patients often stay in the hospital for a few hours after this procedure, though sometimes an overnight stay is necessary.

Before Your Ovarian Biopsy

Preparation for an ovarian biopsy involves several steps to ensure the procedure’s safety and effectiveness. Patients typically have a pre-procedure consultation with their healthcare team to review their medical history and discuss the biopsy details, providing an opportunity to ask questions and understand what to expect.

Medical tests are often performed beforehand, including blood work to assess overall health and kidney function, as well as imaging scans to precisely locate the area for biopsy. It is important to inform the healthcare team about all medications, vitamins, and herbal supplements being taken. Patients are usually instructed to stop certain medications, especially blood thinners, to reduce the risk of bleeding. Fasting instructions are common, requiring patients to avoid eating or drinking for a specific period before the biopsy, especially if general anesthesia or sedation will be used. Planning for transportation home after the procedure is also necessary, as patients may not be able to drive due to the effects of anesthesia or sedation.

After Your Ovarian Biopsy

Following an ovarian biopsy, patients can expect a period of recovery during which they may experience certain symptoms. Mild to moderate pain or discomfort around the surgical site is common, which can often be managed with over-the-counter pain relievers or prescribed medication. Some individuals might experience abdominal soreness or bloating, depending on the biopsy method used.

Activity restrictions are typically advised to allow for proper healing. Patients are usually encouraged to rest for the first few days and gradually return to their normal activities as tolerated. Strenuous activities, heavy lifting, and intense exercise are generally restricted for a few weeks to prevent complications.

Wound care instructions will be provided, especially for surgical biopsies, to prevent infection and promote healing of the incision sites. Patients should monitor for signs of infection, such as increased redness, swelling, pus, or fever, and contact their healthcare provider if these occur. Results from the biopsy typically become available within a week to 10 days, but this timeline can vary. The healthcare team will discuss the findings and outline any necessary next steps.