Ginkgo biloba is an herbal supplement derived from the leaves of the Ginkgo tree. Its extracts have a long history of use in traditional medicine, particularly in Chinese herbal practices, for various health conditions. The supplement is often explored for its potential effects on cognitive function and circulation.
Dosage Recommendations for Specific Conditions
For supporting cognitive function and addressing age-related cognitive decline, a common dosage for standardized ginkgo biloba extract, such as EGb 761, is 120 to 240 milligrams per day, often divided into two or three doses. This range is frequently studied in research related to mild cognitive impairment and dementia.
For tinnitus, particularly when associated with age or dementia, a daily dose of 240 milligrams of EGb 761 has been shown to alleviate symptoms. This dosage is often administered in divided doses. EGb 761 is an approved medication for tinnitus in several countries.
For peripheral artery disease (PAD), which involves reduced blood flow to the limbs, dosages ranging from 120 to 240 milligrams of standardized ginkgo biloba extract per day have been used in research. Studies indicate that EGb 761 may increase pain-free walking distance in individuals with PAD. These dosages are general guidelines, and it is advisable to consult a healthcare professional for personalized advice.
Forms and Administration
Ginkgo biloba is available in several forms, including capsules, tablets, and liquid extracts. The most commonly studied and recommended form is a standardized extract, such as EGb 761. This standardization ensures each dose contains consistent levels of active compounds, primarily ginkgo flavone glycosides (22-27%) and terpene lactones (5-7%), including ginkgolides and bilobalide.
Taking ginkgo biloba with food is recommended to minimize digestive upset. The effects of ginkgo biloba are not immediate and may take several weeks or months of consistent use to become noticeable. For instance, some studies on cognitive benefits involve treatment periods of at least 20 weeks.
Factors Influencing Individual Dosage
Individual responses to ginkgo biloba can vary due to several factors. Age is one consideration, as older adults might have different metabolic rates or sensitivities to supplements. Overall health status, including existing medical conditions, can also affect how an individual responds to ginkgo biloba.
Individual physiological responses, such as how the body absorbs and processes the supplement, also play a role in determining optimal dosage. A healthcare professional can assess these factors and provide tailored recommendations. This personalized approach helps ensure effectiveness and safety.
Potential Side Effects and Drug Interactions
Ginkgo biloba has a favorable safety profile, but it can cause some side effects. Common side effects include digestive upset, headaches, dizziness, and allergic skin reactions. More serious side effects can involve increased bleeding risk.
Ginkgo biloba can interact with various medications. It affects blood clotting and should be used with caution, or avoided, by individuals taking anticoagulant or antiplatelet medications, such as warfarin, aspirin, or clopidogrel, due to an increased risk of bleeding. It may also interact with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen.
Interactions with antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), are also possible, potentially leading to serotonin syndrome in rare cases. Individuals with diabetes should monitor their blood sugar levels closely, as ginkgo biloba might affect glucose metabolism. Pregnant or breastfeeding individuals, those with bleeding disorders, or anyone scheduled for surgery should avoid ginkgo biloba due to the potential for increased bleeding. Consulting a healthcare provider before starting any new supplement is advisable, especially if other medications are being taken or pre-existing conditions are present.