What Causes Excessive Fetal Growth? Risks and Management

Excessive fetal growth, where a baby is significantly larger than average, presents unique challenges during pregnancy and delivery. While fetal growth is generally healthy, growth exceeding normal parameters can complicate the birthing process for both the mother and the newborn. Understanding the causes and potential risks associated with an oversized fetus is important for proactive management and ensuring the safest possible outcome.

Defining and Diagnosing Excessive Fetal Growth

Excessive fetal growth is described by two medical terms: fetal macrosomia and Large for Gestational Age (LGA). Fetal macrosomia refers to an absolute birth weight exceeding a specific threshold, typically 4,000 grams (about 8 pounds, 13 ounces) or, in some practices, 4,500 grams (about 9 pounds, 15 ounces). LGA is a relative measurement, meaning the estimated fetal weight is above the 90th percentile for the baby’s current gestational age. Both terms describe a baby whose size is medically concerning due to potential delivery complications.

Diagnosing this condition before birth relies on estimating the fetal weight (EFW) through ultrasound measurements and assessing the maternal fundal height. However, these prenatal assessments are imprecise, with accuracy decreasing as the baby’s size increases. The only definitive diagnosis of macrosomia is made after birth by weighing the newborn. Identifying risk factors and growth trends remains important for delivery planning despite the limitations of prenatal estimation.

Primary Factors Driving Oversize

The most significant factor contributing to excessive fetal growth is uncontrolled or pre-existing maternal diabetes, including both pre-gestational and gestational diabetes. When maternal blood sugar levels are high, glucose crosses the placenta to the fetus. This triggers the fetal pancreas to release large amounts of insulin (fetal hyperinsulinemia), which acts as a powerful growth hormone. This stimulates nutrient uptake and accelerates the accumulation of body fat, resulting in generalized overgrowth. This overgrowth is often characterized by disproportionately increased fat deposits around the shoulders and trunk.

Maternal obesity and excessive weight gain during pregnancy also promote fetal overgrowth. A high maternal body mass index (BMI) before conception and gaining weight above recommended guidelines provide an increased nutrient supply to the developing fetus. This excess energy intake, independent of diabetes, can lead to a larger baby. Women who have previously delivered a macrosomic baby are more likely to do so again, suggesting a strong metabolic predisposition.

Other contributing factors include prolonged gestation, which allows more time for continued growth. High parity, meaning a woman has had many previous births, also increases the risk, as subsequent babies tend to be larger than the first. The combination of maternal glucose and weight status determines the likelihood and extent of excessive fetal growth.

Immediate Risks During Labor and Delivery

The primary concern associated with excessive fetal size is the increased risk of complications from the physical difficulty of passing a large body through the birth canal. The most serious fetal complication is shoulder dystocia, where the baby’s head delivers but the anterior shoulder becomes lodged behind the mother’s pubic bone. Shoulder dystocia requires immediate, skilled maneuvers to free the baby and is associated with a high risk of birth trauma.

Birth trauma to the baby can include a fractured clavicle or injury to the brachial plexus, the nerves running from the neck to the arm. This nerve injury can result in temporary or permanent weakness or paralysis in the baby’s arm. Babies born of diabetic mothers are also at risk for neonatal hypoglycemia, a sharp drop in blood sugar after birth. This occurs due to their continued high insulin production in the absence of the maternal glucose supply, requiring close monitoring and prompt intervention.

For the mother, delivering a large baby increases the likelihood of a Cesarean section due to labor arrest or failure to progress. A large fetus also raises the risk of uterine atony, where the uterus fails to contract adequately after birth, causing postpartum hemorrhage (excessive bleeding). The physical strain can also cause severe perineal lacerations or tearing of the vaginal tissues.

Management Approaches Before and During Birth

Managing a pregnancy with suspected excessive fetal growth begins with optimizing maternal health factors throughout the antenatal period. For women with pre-existing or gestational diabetes, strict control of blood sugar levels is the most effective strategy to limit fetal overgrowth. This involves dietary changes, regular physical activity, and sometimes insulin therapy to keep glucose within a healthy range. For all expectant mothers, managing gestational weight gain through nutritional counseling and exercise is recommended to mitigate the risk of macrosomia.

Decisions regarding the timing and mode of delivery are guided by the estimated fetal weight and the presence of maternal diabetes. Attempting a vaginal delivery is generally considered safe for non-diabetic women if the estimated fetal weight is below 5,000 grams. A prophylactic Cesarean section may be considered for non-diabetic women when the estimated weight exceeds 5,000 grams due to the increased risk of shoulder dystocia. For women with diabetes, the threshold for a planned Cesarean delivery is lower, typically at an estimated fetal weight of 4,500 grams. During labor, preparation for potential shoulder dystocia is standard procedure for all deliveries involving a suspected large baby.