Nattokinase, an enzyme derived from a traditional Japanese food, has gained attention as a health supplement. Its potential role in addressing various health conditions, including erectile dysfunction (ED), is of particular interest. This article explores the connection between nattokinase and erectile function, examining its properties and current scientific understanding.
What is Nattokinase?
Nattokinase is an enzyme extracted from natto, a fermented soybean dish and dietary staple in Japan for centuries. The fermentation process, involving the bacterium Bacillus subtilis natto, produces this enzyme. Natto is known for its distinct sticky texture, pungent aroma, and various health benefits.
Nattokinase’s primary activity is breaking down fibrin, a protein central to blood clot formation. This fibrinolytic property leads to its marketing for cardiovascular health. It directly hydrolyzes fibrin and enhances the body’s natural clot-dissolving mechanisms.
How Nattokinase Could Influence Erectile Function
Erectile dysfunction is frequently associated with impaired blood flow to the penis. Achieving and maintaining an erection relies on healthy vascular function and adequate circulation. Nattokinase’s fibrinolytic activity suggests theoretical pathways for supporting erectile function.
By breaking down fibrin, nattokinase could improve blood flow by reducing blood viscosity and dissolving micro-clots. Improved blood flow is fundamental for penile engorgement and erection. Beyond its direct clot-dissolving effects, nattokinase also offers cardiovascular benefits like supporting blood pressure regulation and anti-platelet effects. These broader circulatory improvements could indirectly contribute to healthier erectile function.
Scientific Findings on Nattokinase and ED
Direct scientific studies investigating nattokinase as an erectile dysfunction treatment are limited. Its fibrinolytic action may promote blood flow to reproductive organs, but this is a theoretical benefit related to overall vascular health, not a proven direct treatment. Comprehensive clinical trials focusing solely on nattokinase and ED are largely lacking.
However, research into nattokinase’s effects on the broader cardiovascular system provides context. Studies indicate it can help lower systolic and diastolic blood pressure, particularly in individuals with hypertension. It also reduces plasma fibrinogen levels and can prevent blood clot formation. These general improvements in blood circulation and vascular health are relevant because healthy blood flow is a prerequisite for erectile function.
Nattokinase supports healthy blood flow and reduces atherosclerosis risk. While these cardiovascular benefits are well-documented, direct evidence proving nattokinase’s efficacy specifically for treating ED is still needed. The connection relies on the assumption that improving overall circulatory health will translate to improved erectile function, but this specific application requires more dedicated research.
Safety Profile and Important Considerations
Nattokinase is generally well-tolerated as a supplement, with few reported side effects like mild digestive upset. However, crucial considerations exist regarding its interaction with medications.
Given its fibrinolytic properties, nattokinase can increase bleeding risk, particularly when combined with blood-thinning medications such as warfarin, aspirin, or other antiplatelet drugs. This combination could lead to increased bruising and bleeding. Discontinue nattokinase at least two weeks before any scheduled surgery, including dental procedures, to minimize bleeding risk. Individuals with bleeding disorders should use caution. Always consult a healthcare professional before starting nattokinase, especially with existing health conditions or other medications.