Naltrexone is a medication primarily used to support individuals in their recovery from alcohol use disorder and opioid use disorder. It is an important part of a comprehensive treatment plan that often includes counseling and other support programs. This medication works to reduce cravings and block the euphoric effects associated with these substances.
Naltrexone and Diarrhea
Diarrhea is a recognized and common side effect for individuals taking Naltrexone. Many patients report gastrointestinal issues, including diarrhea, when starting the medication. While the severity can vary, it is considered a mild side effect that often improves as the body adjusts to the medication.
How Naltrexone Affects Digestion
Naltrexone functions as an opioid antagonist, blocking opioid receptors in the body. These receptors are found extensively throughout the gastrointestinal tract. Opioid receptors in the gut regulate processes like gut motility (the movement of food through the digestive system) and fluid secretion. By blocking these receptors, Naltrexone can disrupt normal digestive signaling. This interference can lead to changes in bowel movements, potentially resulting in increased gut activity and diarrhea.
Managing Digestive Discomfort
To manage Naltrexone-induced diarrhea, several strategies can help. Staying well-hydrated by drinking plenty of fluids, such as water or electrolyte-rich drinks, is important to prevent dehydration. Adjusting your diet to include bland, easy-to-digest foods like bananas, rice, applesauce, and toast, often referred to as the BRAT diet, can also be beneficial. Eating smaller, more frequent meals throughout the day may also reduce gastrointestinal upset. Taking Naltrexone with food can help minimize stomach discomfort and nausea.
Over-the-counter remedies for diarrhea can be considered, but consult with a healthcare provider before starting any new medication. It is important not to discontinue Naltrexone without medical advice, even if experiencing side effects.
Other Potential Side Effects
Beyond diarrhea, Naltrexone can cause other common side effects as the body adjusts to the medication. These include nausea, headaches, dizziness, fatigue, insomnia, anxiety, nervousness, abdominal pain, and cramping. These mild side effects often lessen over the first few days to weeks of treatment.
When to Consult a Healthcare Provider
It is important to contact a healthcare provider if diarrhea or other side effects become severe or persistent. Seek medical attention if you experience signs of dehydration, such as decreased urination, extreme thirst, or dizziness upon standing. Any signs of severe abdominal pain, blood in the stool, or symptoms that significantly impact your daily life warrant immediate medical consultation. Your healthcare provider can assess your symptoms and determine if any adjustments to your treatment plan are necessary.