Does Monkeypox Scar? What to Know About Lesions and Healing

Monkeypox is a viral disease characterized by a distinctive rash that progresses through several stages. While the infection resolves on its own, a common concern is the potential for lasting skin changes. Scarring is a possible outcome for those who experience monkeypox, with the extent and appearance of these scars varying significantly from person to person. This article explores the process of lesion development, factors influencing scar formation, the typical appearance of monkeypox scars, and strategies for minimizing and managing them.

Understanding Monkeypox Lesions and Scarring

Monkeypox manifests with lesions that undergo a predictable progression. Initially, these lesions may appear as flat, discolored spots known as macules, which then develop into small, raised bumps called papules. These papules can evolve into fluid-filled blisters, or vesicles, and then pus-filled lesions, known as pustules. The final stage involves the formation of scabs or crusts, which eventually fall off as the skin heals.

Scarring occurs when the inflammatory process of these lesions extends into the deeper layers of the skin, specifically the dermis. When this deeper tissue is damaged, the body’s natural repair mechanisms produce new collagen fibers, which can result in a scar rather than regenerated skin. The severity and depth of the damage from the monkeypox lesions play a significant role in determining whether a scar will form.

Factors Affecting Scar Formation

Several elements can influence the likelihood and severity of scar formation. The depth and extent of the lesions are primary determinants; more severe or deeper lesions are more prone to scarring. Secondary bacterial infections significantly increase inflammation and tissue damage, thereby heightening the risk of more pronounced scarring.

Mechanical trauma, such as scratching, rubbing, or picking at the scabs, disrupts the healing process and can lead to deeper tissue injury, contributing to more noticeable scars. Individual biological factors, including skin type and genetic predisposition, also play a part. The location of the lesions on the body can also affect scar appearance, with areas like the face, genitals, and mucosal membranes sometimes experiencing more prominent scarring.

Appearance of Monkeypox Scars

Monkeypox scars can manifest in various forms, reflecting how skin heals after damage. One common type is atrophic scars, which appear as pitted or sunken areas, similar to those seen after chickenpox or severe acne. These occur when there is a loss of tissue during the healing process.

Some individuals may develop hypertrophic scars, which are raised and reddish, but remain within the boundaries of the original lesion. A more extreme form of raised scarring is keloid scars, characterized by an overgrown, firm, and often discolored appearance that extends beyond the initial wound site. These can be red or purple initially, later becoming brown or pale. Beyond changes in texture, monkeypox can also cause pigmentary changes, including post-inflammatory hyperpigmentation (darkening of the skin) or hypopigmentation (lightening of the skin) in the affected areas.

Minimizing and Managing Scars

Effective care during the infection can help minimize the potential for scarring. Keeping the affected areas clean with mild soap and water is important to prevent secondary bacterial infections. Applying a thin layer of petrolatum-based ointment and keeping lesions covered can soothe the rash, promote healing, and protect the skin. Avoiding scratching or picking at the lesions is important, as this can worsen tissue damage and increase the risk of scarring.

After the lesions have healed, protecting new skin from sun exposure is beneficial, as sunlight can exacerbate discoloration. Regular use of a broad-spectrum sunscreen with an SPF of 30 or higher is recommended for several months. For existing scars, over-the-counter options like silicone gels or sheets can help flatten and soften raised scars. Topical creams containing ingredients like aloe vera or ceramides can keep the skin moisturized, which aids in healing. For more persistent or noticeable scars, dermatologists offer various treatments:

  • Laser therapy to reduce redness and improve texture.
  • Steroid injections for raised scars.
  • Microneedling and chemical peels for pitted scars.
  • Surgical revision.