Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) prescribed to alleviate pain and inflammation often associated with conditions like arthritis. Many individuals seeking relief from such discomfort often wonder about potential side effects, including changes in body weight.
Does Meloxicam Cause Weight Gain?
While meloxicam is not typically associated with an increase in body fat, it can lead to fluid retention, which may show as an increase on the scale. This fluid retention is a known side effect across the class of nonsteroidal anti-inflammatory drugs. Specifically, studies suggest that weight gain is a rare occurrence, affecting less than 2% of people taking meloxicam. However, fluid retention itself can be more common, observed in 0.6% to 4.5% of individuals in clinical studies. It is important to distinguish this temporary increase in scale weight due to water accumulation from actual fat gain.
Understanding Fluid Retention
Meloxicam, like other NSAIDs, can cause fluid retention by affecting kidney function. These medications can interfere with the kidneys’ ability to properly excrete sodium and water, leading to their accumulation within the body. This mechanism involves the inhibition of prostaglandins, which are hormone-like substances that help regulate kidney function. Symptoms of fluid retention can include swelling in various body parts, commonly the ankles, feet, or hands. Individuals might also notice general puffiness, a feeling of bloating, or a rapid weight gain over a few days or weeks. When pressed, the swollen skin might temporarily hold an indent, a sign known as pitting edema.
What to Do About Weight Changes
Individuals who notice weight changes while taking meloxicam should monitor their symptoms, such as any swelling or puffiness. It is important to discuss these observations with a healthcare provider. Your doctor can evaluate the cause of the weight changes and determine if they are related to the medication or other factors. Adjustments to medication or the implementation of specific management strategies might be necessary. Healthcare providers may recommend lifestyle factors to help manage fluid retention, such as avoiding excessive sodium in the diet. Elevating swollen limbs and engaging in light exercise can also be beneficial. It is crucial to never discontinue meloxicam without first consulting a doctor, as doing so can have serious health consequences.