Does Losartan Cause Heart Palpitations?

Losartan (Cozaar) is primarily prescribed to manage high blood pressure (hypertension). It belongs to a class of drugs called Angiotensin II Receptor Blockers (ARBs), which relax blood vessels and improve blood flow. Losartan also reduces stroke risk in individuals with high blood pressure and an enlarged heart, and protects kidneys in patients with type 2 diabetes and kidney disease.

Understanding Palpitations

Heart palpitations are sensations where an individual becomes acutely aware of their heartbeat. These feelings can manifest as a pounding, fluttering, or racing heart, or the perception of skipped or extra beats. While often unsettling and frequently harmless, palpitations can sometimes indicate a more significant health issue, making it important to understand their potential causes.

Losartan and Palpitations: The Connection

Losartan works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow. By blocking angiotensin II receptors, Losartan leads to the relaxation of blood vessels, which in turn lowers blood pressure and reduces the workload on the heart. This mechanism of action is primarily focused on vascular tone and blood pressure regulation rather than directly affecting the heart’s electrical rhythm.

While Losartan is generally well-tolerated, heart palpitations are not commonly reported as a direct or frequent side effect. Rare instances of irregular heartbeat or rapid heart rate have been reported. If palpitations occur while taking Losartan, they are more likely indirect or related to other factors, such as electrolyte imbalances. Losartan can sometimes lead to an increase in blood potassium levels (hyperkalemia), which in severe cases may manifest as heart palpitations or irregular heartbeats.

Other Potential Causes of Palpitations

Many factors unrelated to Losartan can trigger heart palpitations. Lifestyle elements frequently contribute to these sensations. Stress, anxiety, and panic attacks are common emotional triggers that can lead to palpitations. Consuming caffeine, nicotine, or alcohol, and engaging in strenuous exercise can also induce palpitations. Dehydration is another lifestyle factor that can cause the heart to feel as though it is fluttering or pounding.

Beyond lifestyle, various medical conditions and other medications can also be responsible for palpitations. Thyroid disorders, such as an overactive thyroid, can lead to an elevated heart rate and palpitations. Anemia, low blood sugar, and certain heart rhythm problems (arrhythmias) are also known causes. Some over-the-counter and prescription medications, including certain asthma inhalers, cold and cough medicines containing stimulants, and even some herbal supplements, can trigger palpitations.

When to Seek Medical Advice

If you experience heart palpitations while taking Losartan, consult a healthcare professional. While often harmless, certain accompanying symptoms warrant immediate medical attention. These warning signs include chest pain or pressure, shortness of breath, dizziness, lightheadedness, or fainting. If palpitations occur frequently, worsen over time, or last longer than a few minutes, seeking medical advice is also recommended.

Do not discontinue Losartan or any other prescribed medication without first consulting your doctor. Your healthcare provider can assess your symptoms, consider other potential causes, and determine the most appropriate course of action. This may include adjusting your medication or conducting further diagnostic tests. Regular monitoring of blood pressure, kidney function, and electrolyte levels, especially potassium, is often part of ongoing care for individuals taking Losartan.