Does Hydrogen Peroxide Get Rid of Cold Sores?

Cold sores, also known as fever blisters, are common viral outbreaks that typically appear on or around the lips and mouth. These small, fluid-filled blisters are caused by the herpes simplex virus (HSV), most often herpes simplex virus type 1 (HSV-1). Once infected, the virus remains dormant in the body and can reactivate periodically, leading to recurring outbreaks. Many people wonder about home remedies for these bothersome sores, and one frequently considered option is hydrogen peroxide.

Hydrogen Peroxide and Cold Sores: The Evidence

Hydrogen peroxide functions as an oxidizing agent and is recognized for its antiseptic qualities. It works by releasing oxygen, which helps cleanse wounded areas. While it has some antiviral properties against certain enveloped viruses, its effectiveness against the herpes simplex virus (HSV) that causes cold sores is not established. HSV, a double-stranded DNA virus, has mechanisms, such as an internal catalase enzyme, that can protect it from hydrogen peroxide.

Therefore, hydrogen peroxide does not eliminate HSV, nor does it treat the underlying viral infection or accelerate healing. While it might clean the sore’s surface, potentially reducing secondary bacterial infections, it does not address the viral cause or speed recovery.

Safe Practices and Potential Risks

Using hydrogen peroxide on delicate skin, such as that around a cold sore, carries several risks. Modern wound care practices no longer recommend its use due to potential harm to healthy tissue. Hydrogen peroxide’s reactive power is not specific to harmful microorganisms; it can also damage healthy skin cells and immune cells important for the healing process.

Applying hydrogen peroxide can irritate the skin, cause burning, and delay natural healing. Damage to healthy cells can prolong the sore’s resolution and may even worsen it. For minor cuts, health professionals now advise simple cleaning with soap and water, as hydrogen peroxide can be detrimental to proper wound healing.

Effective Alternatives for Cold Sore Relief

For managing cold sores, several effective and scientifically supported alternatives are available. Antiviral medications are the most common and effective treatment. These can be topical, such as creams containing acyclovir, penciclovir, or docosanol, or oral medications like acyclovir, valacyclovir, and famciclovir. These medications work by inhibiting the virus’s ability to multiply, which can help reduce symptoms and accelerate healing, particularly when started at the first sign of an outbreak.

Beyond antiviral treatments, other remedies can provide symptomatic relief. Over-the-counter pain relievers, cold compresses, and topical gels containing numbing agents like benzocaine or lidocaine can help alleviate discomfort. Some individuals also find relief with soothing topical applications like aloe vera gel, lysine supplements, or propolis cream, which may help with symptom management and support healing.