Does HCG Cause Diarrhea, or Is Something Else to Blame?

Human chorionic gonadotropin (HCG) is a hormone naturally produced in the body, most notably during pregnancy. It is also utilized in medical treatments, such as fertility therapies, and has been controversially applied in certain weight loss regimens. This article clarifies the relationship between HCG and diarrhea, exploring contexts where the hormone is present and identifying other factors that might contribute to digestive upset.

Understanding HCG and Its Contexts

Human chorionic gonadotropin is a hormone primarily produced by trophoblast cells, which surround a developing embryo and eventually form the placenta. In early pregnancy, HCG signals the body to maintain the corpus luteum, which produces progesterone to support the uterine lining and the growing fetus. HCG levels rise rapidly in the first trimester, typically doubling every two to three days, before gradually decreasing. This hormone is what pregnancy tests detect.

Beyond its natural role, synthetic HCG is administered for various medical purposes. In fertility treatments, HCG injections can induce ovulation in females, often called a “trigger shot.” It can also support testosterone production in males or help with undescended testicles in pre-pubescent boys. HCG has also been used in controversial weight loss protocols, known as the HCG diet, which combines HCG administration with an extremely low-calorie intake, often around 500 calories per day.

HCG and Diarrhea: A Direct Link?

Diarrhea is generally not considered a common or direct side effect of HCG, whether naturally produced or medically administered. Clinical observations typically do not list diarrhea as a prominent direct side effect. However, it is a less common side effect associated with Ovarian Hyperstimulation Syndrome (OHSS), a serious condition that can occur during fertility treatments involving HCG.

In cases of OHSS, symptoms can include severe pelvic or stomach pain, bloating, nausea, vomiting, rapid weight gain, and sometimes diarrhea. This condition is a response to the ovaries becoming overstimulated by hormones, including HCG, leading to fluid shifts and other complications.

Common Causes of Diarrhea in HCG-Related Situations

While HCG is not a direct cause of diarrhea in most instances, other contributing factors are likely present when HCG is in the body, such as during pregnancy or the HCG diet. During pregnancy, various physiological changes can affect the gastrointestinal tract. Hormonal shifts, particularly increased progesterone levels, can relax smooth muscles in the digestive system, slowing digestion and affecting bowel regularity.

Dietary changes, increased sensitivity to certain foods, or morning sickness are common in early pregnancy and can sometimes lead to digestive upset, including diarrhea. Pressure from the growing uterus can also impact bowel function.

For those following the HCG diet, diarrhea is more frequently attributed to the extremely low-calorie diet rather than the HCG hormone itself. Consuming only 500 calories per day can drastically alter the digestive biome and lead to gastrointestinal distress. Severe dietary restrictions, changes in food types, and potential dehydration can disrupt normal bowel function. Diarrhea can also be caused by various unrelated factors such as infections, food intolerances, stress, or other medications, which could coincidentally occur when HCG is present.

When to Seek Medical Advice

Experiencing diarrhea, especially if persistent or severe, warrants medical attention regardless of whether HCG is involved. If diarrhea lasts for more than a couple of days without improvement, or if it is accompanied by concerning symptoms, consulting a healthcare professional is important. Signs indicating a need for prompt medical evaluation include severe abdominal pain, fever, or bloody or black stools.

Signs of dehydration, such as excessive thirst, decreased urination, dizziness, or lightheadedness, also require immediate medical attention, as dehydration can be a serious complication of diarrhea. If undergoing fertility treatments, severe bloating, stomach pain, rapid weight gain, nausea, vomiting, or diarrhea could signal Ovarian Hyperstimulation Syndrome (OHSS), requiring urgent medical assessment. A healthcare provider can determine the underlying cause and recommend appropriate treatment.