Does Chemotherapy Cause Weight Gain? And How to Manage It

For many individuals facing cancer treatment, the expectation is often weight loss. However, a surprising and distressing side effect for some undergoing chemotherapy is weight gain. This challenges common perceptions of cancer and its treatments. Understanding the various factors contributing to this phenomenon is important for patients.

Reasons for Weight Gain During Chemotherapy

Several factors contribute to weight gain during chemotherapy, including prescribed medications, shifts in daily habits, and emotional responses. Corticosteroids like Dexamethasone, commonly used to manage nausea and inflammation, can stimulate appetite. These powerful drugs also alter metabolism, sometimes causing fat redistribution to areas like the abdomen, face, and neck.

Treatment-related fatigue, nausea, pain, and other side effects often reduce physical activity. Low energy levels make it challenging to maintain exercise routines, leading to fewer calories burned. This decreased energy expenditure, combined with potential increases in calorie intake, can contribute to weight gain.

Chemotherapy can also induce changes in diet and eating habits. Patients may experience altered taste or increased cravings for “comfort” foods, often high in sugar or calories, to combat nausea or cope with stress. Irregular meal times or frequent eating due to boredom or emotional factors can further imbalance calorie intake and expenditure.

The body’s metabolism may also undergo changes during chemotherapy. Some chemotherapy drugs, along with hormonal therapies often used for certain cancers like breast or prostate, can temporarily slow metabolic rate. A reduced metabolism means the body uses fewer calories, potentially leading to weight gain even if dietary intake remains consistent. Stress, anxiety, and depression from a cancer diagnosis and treatment can also trigger emotional eating.

Understanding Fluid Retention

Beyond true fat gain, a common and often confusing contributor to weight increase during chemotherapy is fluid retention, also known as edema. This occurs when the body retains excess fluid in its tissues, leading to swelling. Certain chemotherapy drugs and corticosteroids can cause this effect by impacting kidney function or capillary permeability.

Fluid retention typically manifests as swelling in the hands, feet, ankles, and face, and patients may also feel bloated. Jewelry might feel tighter, and there could be a noticeable decrease in flexibility in affected limbs. This type of weight gain differs from an increase in body fat.

Recognizing this distinction is important for patients, as the weight on the scale might not solely represent adipose tissue. While fluid retention contributes to overall body weight, it often resolves after treatment concludes or can be managed with specific medical interventions. Understanding this can alleviate concerns about dietary restrictions for fat loss, as the primary issue is fluid balance, not caloric excess.

Managing Weight During Treatment

Managing weight during chemotherapy requires a careful, individualized approach, emphasizing healthy practices over drastic measures. It is important to consult with the healthcare team, including doctors, nurses, or registered dietitians specializing in oncology nutrition, before implementing any significant dietary or exercise changes. They provide personalized guidance based on the specific chemotherapy regimen and individual health status.

Adopting balanced dietary strategies can be beneficial. Focusing on nutrient-dense foods, such as lean proteins, whole grains, fruits, and vegetables, can help provide necessary nutrients without excessive calories. Practicing mindful eating and controlling portion sizes also supports weight management. Limiting sugary drinks and highly processed foods, which often contribute to weight gain, is advisable.

When medically cleared, gentle physical activity can help manage weight and improve well-being. Activities like short walks or stretching can boost energy levels and support muscle mass maintenance. Even light movement can counteract reduced activity due to fatigue, contributing positively to metabolic health.

Maintaining adequate hydration is also important, even for those experiencing fluid retention. While seemingly counterintuitive, proper fluid intake can help the body manage fluid balance more effectively. Seeking emotional support through counseling or support groups can address emotional eating triggers, providing healthy coping mechanisms for stress and anxiety related to treatment. Monitoring weight regularly, but not obsessively, and reporting significant or rapid changes to the healthcare team ensures any concerns are addressed promptly.